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GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase 
Summary
GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase (EC 2.4.1.293, PglI) is an enzyme with systematic name UDP-alpha-D-glucose:(GalNAc-alpha-(1->4))4-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol 3-beta-D-glucosyltransferase.[1][2] This enzyme catalyses the following chemical reaction
| GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.293 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- UDP-alpha-D-glucose + [GalNAc-alpha-(1->4)]4-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol UDP + [GalNAc-alpha-(1->4)]2-[Glc-beta-(1->3)]-[GalNAc-alpha-(1->4)]2-GalNAc-alpha-(1->3)-diNAcBac-diphospho-tritrans,heptacis-undecaprenol
This enzyme is isolated from the bacterium Campylobacter jejuni.
References edit
- ^ Glover KJ, Weerapana E, Imperiali B (October 2005). "In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation". Proceedings of the National Academy of Sciences of the United States of America. 102 (40): 14255–9. doi:10.1073/pnas.0507311102. PMC 1242339. PMID 16186480.
- ^ Kelly J, Jarrell H, Millar L, Tessier L, Fiori LM, Lau PC, Allan B, Szymanski CM (April 2006). "Biosynthesis of the N-linked glycan in Campylobacter jejuni and addition onto protein through block transfer". Journal of Bacteriology. 188 (7): 2427–34. doi:10.1128/JB.188.7.2427-2434.2006. PMC 1428418. PMID 16547029.
External links edit
- GalNAc5-diNAcBac-PP-undecaprenol+beta-1,3-glucosyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
