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Ganesh Bagler

Summary

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Ganesh Bagler is known for his research [1][2][3][4][5][6][7][8][9][10] in computational gastronomy, an emerging data science of food, flavors and health.[11][12][13] By blending food with data and computation he has helped establish the foundations of this niche area.[11][12][9][7] Starting with the investigation of food pairing in the Indian cuisine,[14][15][16][17][18][19][20] his lab has contributed to computational gastronomy with studies on culinary fingerprints of world cuisines,[4] culinary evolution,[21][22] benevolent health impacts of spices,[23] and taste prediction algorithms.[3]

Ganesh Bagler
Born (1977-01-31) 31 January 1977 (age 47)
Solapur, Maharashtra, India
Alma mater
Known for
  • Pioneering work in computational gastronomy
  • Science and education
Scientific career
FieldsComputational biology
Institutions
Websitecosylab.iiitd.edu.in

Education edit

Bagler completed his schooling from Sharada School and Siddheshwar High School, Solapur in the western peninsular Indian state of Maharashtra. He did his graduation in Physics (B.Sc., 1997) from Sangameshwar College,[24] Shivaji University and master's studies (M.Sc. Physics, 1999) from Savitribai Phule Pune University, Pune. He moved to University of Hyderabad for M.Tech. in Computational Techniques, before joining Centre for Cellular and Molecular Biology for his Ph.D. research in Computational Biology.[25] His Ph.D. research involved investigation of graph theoretical models of protein structures [26][27] which led to the observation of exceptional assortative mixing in graph theoretical models of protein structures.[28]

Career edit

After the postdoctoral research stint in computational neuroscience at the National Centre for Biological Sciences as a visiting fellow,[29] he joined the Max Planck Institute for Molecular Genetics in Prof. Michael Lappe's (Otto Warburg Laboratory, Bioinformatics/Structural Proteomics) group.[30] He returned to India to join CSIR-Institute of Himalayan Bioresource Technology as a Scientist.[31] In April 2013, he moved to Indian Institute of Technology Jodhpur as an assistant professor.[32][33] After a brief stint at Dhirubhai Ambani Institute of Information and Communication Technology as an assistant professor,[34][35][36] he moved to Indraprastha Institute of Information Technology (IIIT-Delhi) on a tenure track position.[37][38][39][40] There, he is affiliated to the Center for Computational Biology [41] and Department of Computational Biology [42] and has been developing the Computational Gastronomy niche in his lab, the Complex Systems Laboratory.[43]

Research edit

Ganesh Bagler's research [44] has been rooted in investigation of complex systems,[43] primarily of biological origin: protein structure-function,[45] kinetics,[46] folding,[47] and design;[48] complex network models transportation systems;[49] molecular interactome models of complex diseases;[50][51] controllability of biological networks;[52][53] in silico drug discovery;[54][55][56][57][58] systems biological investigation of brain networks;[59][60][61][62] modeling and prediction of phenotypic side effects of drugs;[63][64] computational models of biological systems;[65][66] and computational gastronomy.[1][2][3][4][5][6][7][8][9][10]

Science communication and outreach edit

Ganesh Bagler has keen interest in science, technology, engineering, and mathematics (STEM) education and public outreach for communicating science.[67] He has been engaged in propagating the cause of leveraging computational gastronomy for data-driven food innovations on various platforms:[67] TEDx;[68] HasGeek's Kilter 2017;[69] Discussion Meeting on Mathematical and Statistical Explorations in Disease Modeling and Public Health at the International Centre for Theoretical Sciences;[70] 7th IFCA [71] International Chefs Congress;[72][73] IIT Guwahati Research Conclave 2017;[74] GD Goenka University Le Cordon Bleu India's [75] iHOST 2017;[76] Cadence Advanced Technology Talk;[77] 2nd International Meeting on Systems Medicine (Utrecht, Netherlands);[78] Food Safety and Standards Authority of India's (FSSAI) EatRight Mela;[79] Bangalore Science Forum;[80] and SIAL Paris Conference 2019 [citation needed]. He has organized two editions of Computational Gastronomy Symposiums at IIIT-Delhi.[81][13] He conducts the 'Open Computational Gastronomy' course on Google Classroom [82][83]

Controversy edit

In April 2015, soon after his research reporting the food pairing investigation of Indian cuisine was touted as an emerging technology by the MIT Technology Review,[14] Bagler was unceremoniously removed from the position of assistant professor at the Indian Institute of Technology Jodhpur in a controversial decision.[84] The students protested against the decision of termination.[84][85][86][87][88][89][90] Ministry of Human Resource Development constituted a three-member committee for the investigation of the matter.[91] Subsequently, Bagler moved to Indraprastha Institute of Information Technology on a tenure track position [39] and has graduated his PhD students [92] from Indian Institute of Technology Jodhpur. He has been tenured and promoted to the position of Associate Professor[40] at Indraprastha Institute of Information Technology.

Selected bibliography edit

  • Ganesh Bagler; Somdatta Sinha (2005). "Network Properties of Protein Structures". Physica A. 346 (1–2): 27–33. arXiv:q-bio/0408009. Bibcode:2005PhyA..346...27B. doi:10.1016/j.physa.2004.08.046. S2CID 9539809.
  • Ganesh Bagler; Somdatta Sinha (2007). "Assortative mixing in Protein Contact Networks and protein folding kinetics". Bioinformatics. 23 (14): 1760–1767. arXiv:0711.2723. Bibcode:2007arXiv0711.2723B. doi:10.1093/bioinformatics/btm257. PMID 17519248.
  • Ganesh Bagler (2008). "Analysis of Airport Network of India as a complex weighted network". Physica A. 387 (12): 2972–2980. arXiv:cond-mat/0409773. Bibcode:2008PhyA..387.2972B. doi:10.1016/j.physa.2008.01.077. S2CID 119387720.
  • Arun Kumar; Som Dutt; Ganesh Bagler; Paramvir Singh Ahuja; Sanjay Kumar (2012). "Engineering a thermostable superoxide dismutase functional at sub-zero to >50°C, which also tolerates autoclaving". Scientific Reports. 2: 387. Bibcode:2012NatSR...2E.387K. doi:10.1038/srep00387. PMC 3339387. PMID 22548128.
  • Shivalika Pathania; Vinay Radhawa; Ganesh Bagler (2013). "Prospecting for novel plant-derived molecules of Rauvolfia serpentina as inhibitors of Aldose Reductase, a potent drug target for diabetes and its complications". PLOS ONE. 8 (4): e61327. Bibcode:2013PLoSO...861327P. doi:10.1371/journal.pone.0061327. PMC 3629236. PMID 23613832.
  • Kriti Dubey; Bibin G Anand; Ganesh Bagler; PN Navya; HK Daima; Karunakar Kar (2015). "Tyrosine and tryptophan coated gold nanoparticles inhibit amyloid aggregation of insulin". Amino Acids. 47 (12): 2551–2560. doi:10.1007/s00726-015-2046-6. PMID 26193769. S2CID 15410659.
  • Anupam Jain; NK Rakhi; Ganesh Bagler (2015). "Analysis of food pairing in regional cuisines of India". PLOS ONE. 10 (10): e0139539. arXiv:1505.00890. Bibcode:2015PLoSO..1039539J. doi:10.1371/journal.pone.0139539. PMC 4592201. PMID 26430895.
  • Navjot Singh; Ganesh Bagler (2018). Data-driven investigations of culinary patterns in traditional recipes across the world. 34th International Conference on Data Engineering, Paris (DÉCOR). pp. 157–162. arXiv:1803.04343. doi:10.1109/ICDEW.2018.00033. ISBN 978-1-5386-6306-6.
  • Neelansh Garg; Apurup Sethupathy; Rudraksh Tuwani; Rakhi NK; Shubham Dokania; Arvind Iyer; Ayushi Gupta; Shubhra Agrawal; Navjot Singh; Shubham Shukla; Kriti Kathuria; Rahul Badhwar; Rakesh Kanji; Anupam Jain; Avneet Kaur; Rashmi Nagpal; Ganesh Bagler (2018). "FlavorDB: A database of flavor molecules". Nucleic Acids Research. D1 (D1): D1210–D1216. doi:10.1093/nar/gkx957. PMC 5753196. PMID 29059383.
  • Anupam Jain; Ganesh Bagler (2018). "Culinary evolution models for Indian cuisines". Physica A. 503: 170–176. arXiv:1505.00155. Bibcode:2018PhyA..503..170J. doi:10.1016/j.physa.2018.02.176. S2CID 16910527.
  • Rakhi NK; Rudraksh Tuwani; Jagriti Mukherjee; Ganesh Bagler (2018). "Data-driven analysis of biomedical literature suggests broad-spectrum benevolence of culinary herbs and spices". PLOS ONE. 13 (5): e0198030. Bibcode:2018PLoSO..1398030R. doi:10.1371/journal.pone.0198030. PMC 5973616. PMID 29813110.
  • Vandana Ravindran; Jose C. Nacher; Tatsuya Akutsu; Masayuki Ishitsuka; Adrian Osadcenco; V. Sunitha; Ganesh Bagler; Jean-Marc Schwartz; David L. Robertson (2019). "Network controllability analysis of intracellular signalling reveals viruses are actively controlling molecular systems". Scientific Reports. 9 (1): 2066. Bibcode:2019NatSR...9.2066R. doi:10.1038/s41598-018-38224-9. PMC 6375943. PMID 30765882.
  • Rudraksh Tuwani; Nutan Sahoo; Navjot Singh; Ganesh Bagler (2019). Computational models for the evolution of world cuisines. 35th International Conference on Data Engineering, Macau, China (DÉCOR). pp. 85–90. arXiv:1904.10138. doi:10.1109/icdew.2019.00-30. ISBN 978-1-7281-0890-2.

References edit

  1. ^ a b Jain, Anupam; Rakhi N K; Bagler, Ganesh (2015). "Spices form the basis of food pairing in Indian cuisine". arXiv:1502.03815 [physics.soc-ph].
  2. ^ a b Jain, Anupam; n k, Rakhi; Bagler, Ganesh (2015). "Analysis of Food Pairing in Regional Cuisines of India". PLOS ONE. 10 (10): e0139539. arXiv:1505.00890. Bibcode:2015PLoSO..1039539J. doi:10.1371/journal.pone.0139539. PMC 4592201. PMID 26430895.
  3. ^ a b c Tuwani, Rudraksh; Wadhwa, Somin; Bagler, Ganesh (9 May 2019). "BitterSweet: Building machine learning models for predicting the bitter and sweet taste of small molecules". Scientific Reports. 9 (1): 7155. Bibcode:2019NatSR...9.7155T. doi:10.1038/s41598-019-43664-y. PMC 6509165. PMID 31073241.
  4. ^ a b c Bagler, Ganesh; Singh, Navjot (2018). "Data-Driven Investigations of Culinary Patterns in Traditional Recipes Across the World". 2018 IEEE 34th International Conference on Data Engineering Workshops (ICDEW). pp. 157–162. arXiv:1803.04343. doi:10.1109/ICDEW.2018.00033. ISBN 978-1-5386-6306-6. S2CID 4941349.
  5. ^ a b Garg, Neelansh; Sethupathy, Apuroop; Tuwani, Rudraksh; Nk, Rakhi; Dokania, Shubham; Iyer, Arvind; Gupta, Ayushi; Agrawal, Shubhra; Singh, Navjot; Shukla, Shubham; Kathuria, Kriti; Badhwar, Rahul; Kanji, Rakesh; Jain, Anupam; Kaur, Avneet; Nagpal, Rashmi; Bagler, Ganesh (4 January 2018). "FlavorDB: a database of flavor molecules". Nucleic Acids Research. 46 (D1): D1210–D1216. doi:10.1093/nar/gkx957. PMC 5753196. PMID 29059383.
  6. ^ a b Rakhi, N. K.; Tuwani, Rudraksh; Mukherjee, Jagriti; Bagler, Ganesh (2018). "Data-driven analysis of biomedical literature suggests broad-spectrum benefits of culinary herbs and spices". PLOS ONE. 13 (5): e0198030. Bibcode:2018PLoSO..1398030R. doi:10.1371/journal.pone.0198030. PMC 5973616. PMID 29813110.
  7. ^ a b c "Can A Computer Cook Up The Perfect Recipe?". HuffPost India. 16 December 2018.
  8. ^ a b "Food Scientists Say AI Can Give Ayurveda Scientific Rigor". HuffPost India. 5 January 2019.
  9. ^ a b c "The secret ingredient of Indian food". Hindustan Times. 21 April 2018.
  10. ^ a b "Computational Gastronomy: Leveraging food for better health through... by Ganesh Bagler". YouTube. 8 August 2019. Retrieved 23 February 2020.
  11. ^ a b "Data" (PDF). www.currentscience.ac.in. Retrieved 24 February 2020.
  12. ^ a b Mathew, Sunalini (22 January 2019). "The scoop on computational gastronomy". The Hindu – via www.thehindu.com.
  13. ^ a b "One Day Symposium on Computational Gastronomy". IIIT-Delhi. 17 November 2018.
  14. ^ a b arXiv, Emerging Technology from the. "Data Mining Indian Recipes Reveals New Food Pairing Phenomenon". MIT Technology Review.
  15. ^ FerdmanBioBio, Roberto A. Ferdman closeRoberto A. "Scientists have figured out what makes Indian food so delicious". Washington Post.
  16. ^ S, Rukmini (2 March 2015). "Big Data is changing the way we look at food". The Hindu – via www.thehindu.com.
  17. ^ "This is why Indian food is so delicious... - Times of India". Timesofindia.indiatimes.com. 6 December 2015. Retrieved 23 February 2020.
  18. ^ "Why Indian Food Is So Tasty". Time.
  19. ^ "Researchers Explain Why Indian Cuisine Is Exquisite". NPR.org.
  20. ^ "The tastes of India: Spices give Indian food the edge". The Jakarta Post.
  21. ^ Jain, Anupam; Bagler, Ganesh (1 August 2018). "Culinary evolution models for Indian cuisines". Physica A: Statistical Mechanics and Its Applications. 503: 170–176. arXiv:1505.00155. Bibcode:2018PhyA..503..170J. doi:10.1016/j.physa.2018.02.176. S2CID 16910527.
  22. ^ Tuwani, Rudraksh; Sahoo, Nutan; Singh, Navjot; Bagler, Ganesh (2019). "Computational models for the evolution of world cuisines". arXiv:1904.10138 [physics.soc-ph].
  23. ^ Rakhi, N. K.; Tuwani, Rudraksh; Mukherjee, Jagriti; Bagler, Ganesh (2018). "Data-driven analysis of biomedical literature suggests broad-spectrum benefits of culinary herbs and spices". PLOS ONE. 13 (5): e0198030. Bibcode:2018PLoSO..1398030R. doi:10.1371/journal.pone.0198030. PMC 5973616. PMID 29813110.
  24. ^ "Sangameshwar College, Solapur". www.sangameshwarcollege.ac.in.
  25. ^ https://www.ccmb.res.in/news/ann_reports/ar2007_08.pdf[dead link]
  26. ^ Bagler, Ganesh (2007). "Modeling Protein Contact Networks". arXiv:0711.2616 [q-bio.MN].
  27. ^ Your name here (2010). Complex Network Models of Protein Structures: Structural Correlates of Biophysical Properties (9783843358606): Ganesh Bagler: Books. Lap Lambert Academic Publishing GmbH KG. ISBN 978-3843358606.
  28. ^ Bagler, Ganesh; Sinha, Somdatta (2007). "Assortative mixing in Protein Contact Networks and protein folding kinetics". Bioinformatics. 23 (14): 1760–1767. arXiv:0711.2723. Bibcode:2007arXiv0711.2723B. doi:10.1093/bioinformatics/btm257. PMID 17519248.
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  33. ^ "Annual report" (PDF). ir.iitj.ac.in:8080. 2014. Retrieved 24 February 2020.
  34. ^ "DAIICT_AR_2017 AK_291117.indd" (PDF). Retrieved 23 February 2020.
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  42. ^ "Department of Computational Biology - IIIT Delhi". Cb.iiitd.ac.in. Retrieved 23 February 2020.
  43. ^ a b "Complex Systems Lab, IIIT-Delhi". Cosylab.iiitd.edu.in. Retrieved 23 February 2020.
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  45. ^ Bagler, Ganesh; Sinha, Somdatta (1 February 2005). "Network properties of protein structures". Physica A: Statistical Mechanics and Its Applications. 346 (1): 27–33. arXiv:q-bio/0408009. Bibcode:2005PhyA..346...27B. doi:10.1016/j.physa.2004.08.046. S2CID 9539809.
  46. ^ Bagler, Ganesh; Sinha, Somdatta (15 July 2007). "Assortative mixing in Protein Contact Networks and protein folding kinetics". Bioinformatics. 23 (14): 1760–1767. arXiv:0711.2723. Bibcode:2007arXiv0711.2723B. doi:10.1093/bioinformatics/btm257. PMID 17519248.
  47. ^ Lappe, Michael; Bagler, Ganesh; Filippis, Ioannis; Stehr, Henning; Duarte, Jose M; Sathyapriya, Rajagopal (1 August 2009). "Designing evolvable libraries using multi-body potentials". Current Opinion in Biotechnology. 20 (4): 437–446. doi:10.1016/j.copbio.2009.07.008. PMID 19713097.
  48. ^ Kumar, Arun; Dutt, Som; Bagler, Ganesh; Ahuja, Paramvir Singh; Kumar, Sanjay (30 April 2012). "Engineering a thermo-stable superoxide dismutase functional at sub-zero to >50°C, which also tolerates autoclaving". Scientific Reports. 2 (1): 387. Bibcode:2012NatSR...2E.387K. doi:10.1038/srep00387. PMC 3339387. PMID 22548128.
  49. ^ Bagler, Ganesh (1 May 2008). "Analysis of the airport network of India as a complex weighted network". Physica A: Statistical Mechanics and Its Applications. 387 (12): 2972–2980. arXiv:cond-mat/0409773. Bibcode:2008PhyA..387.2972B. doi:10.1016/j.physa.2008.01.077. S2CID 119387720.
  50. ^ Vashisht, Shikha; Bagler, Ganesh (2012). "An Approach for the Identification of Targets Specific to Bone Metastasis Using Cancer Genes Interactome and Gene Ontology Analysis". PLOS ONE. 7 (11): e49401. arXiv:1112.1510. Bibcode:2012PLoSO...749401V. doi:10.1371/journal.pone.0049401. PMC 3498148. PMID 23166660.
  51. ^ Randhawa, Vinay; Bagler, Ganesh (2012). "Identification of SRC as a Potent Drug Target for Asthma, Using an Integrative Approach of Protein Interactome Analysis and in Silico Drug Discovery". OMICS: A Journal of Integrative Biology. 16 (10): 513–526. doi:10.1089/omi.2011.0160. PMID 22775150.
  52. ^ Ravindran, Vandana; Nacher, Jose C.; Akutsu, Tatsuya; Ishitsuka, Masayuki; Osadcenco, Adrian; Sunitha, V.; Bagler, Ganesh; Schwartz, Jean-Marc; Robertson, David L. (14 February 2019). "Network controllability analysis of intracellular signalling reveals viruses are actively controlling molecular systems". Scientific Reports. 9 (1): 2066. Bibcode:2019NatSR...9.2066R. doi:10.1038/s41598-018-38224-9. PMC 6375943. PMID 30765882.
  53. ^ Ravindran, Vandana; V., Sunitha; Bagler, Ganesh (15 May 2017). "Identification of critical regulatory genes in cancer signaling network using controllability analysis". Physica A: Statistical Mechanics and Its Applications. 474: 134–143. Bibcode:2017PhyA..474..134R. doi:10.1016/j.physa.2017.01.059.
  54. ^ Pathania, Shivalika; Randhawa, Vinay; Bagler, Ganesh (2013). "Prospecting for Novel Plant-Derived Molecules of Rauvolfia serpentina as Inhibitors of Aldose Reductase, a Potent Drug Target for Diabetes and Its Complications". PLOS ONE. 8 (4): e61327. Bibcode:2013PLoSO...861327P. doi:10.1371/journal.pone.0061327. PMC 3629236. PMID 23613832.
  55. ^ Pathania, Shivalika; Ramakrishnan, Sai Mukund; Randhawa, Vinay; Bagler, Ganesh (2015). "SerpentinaDB: A database of plant-derived molecules of Rauvolfia serpentina". BMC Complementary and Alternative Medicine. 15: 262. doi:10.1186/s12906-015-0683-7. PMC 4523024. PMID 26238452.
  56. ^ Pathania, Shivalika; Ramakrishnan, Sai Mukund; Bagler, Ganesh (2015). "Phytochemica: A platform to explore phytochemicals of medicinal plants". Database. 2015: bav075. doi:10.1093/database/bav075. PMC 4529746. PMID 26255307.
  57. ^ Dubey, Kriti; Anand, Bibin G.; Badhwar, Rahul; Bagler, Ganesh; Navya, P. N.; Daima, Hemant Kumar; Kar, Karunakar (2015). "Tyrosine- and tryptophan-coated gold nanoparticles inhibit amyloid aggregation of insulin". Amino Acids. 47 (12): 2551–2560. doi:10.1007/s00726-015-2046-6. PMID 26193769. S2CID 15410659.
  58. ^ Perumal, Sathiamurthi; Dubey, Kriti; Badhwar, Rahul; George, Kodimattan Joseph; Sharma, Rakesh Kumar; Bagler, Ganesh; Madhan, Balaraman; Kar, Karunakar (2015). "Capsaicin inhibits collagen fibril formation and increases the stability of collagen fibers". European Biophysics Journal. 44 (1–2): 69–76. doi:10.1007/s00249-014-1002-9. PMID 25528374. S2CID 17862960.
  59. ^ Badhwar, Rahul; Bagler, Ganesh (2015). "Control of Neuronal Network in Caenorhabditis elegans". PLOS ONE. 10 (9): e0139204. Bibcode:2015PLoSO..1039204B. doi:10.1371/journal.pone.0139204. PMC 4586142. PMID 26413834.
  60. ^ Badhwar, Rahul; Bagler, Ganesh (1 March 2017). "A distance constrained synaptic plasticity model of C. elegans neuronal network". Physica A: Statistical Mechanics and Its Applications. 469: 313–322. arXiv:1603.03867. Bibcode:2017PhyA..469..313B. doi:10.1016/j.physa.2016.11.055. S2CID 2795267.
  61. ^ Singh, Megha; Badhwar, Rahul; Bagler, Ganesh (2016). "Network biomarkers of schizophrenia by graph theoretical investigations of Brain Functional Networks". arXiv:1602.01191 [q-bio.QM].
  62. ^ Badhwar, Rahul; Bagler, Ganesh (2017). "Robust Sigmoidal Control Response of C. Elegans Neuronal Network". Rough Sets. Lecture Notes in Computer Science. Vol. 10314. pp. 393–402. doi:10.1007/978-3-319-60840-2_29. ISBN 978-3-319-60839-6.
  63. ^ Kanji, Rakesh; Sharma, Abhinav; Bagler, Ganesh (13 October 2015). "Phenotypic side effects prediction by optimizing correlation with chemical and target profiles of drugs". Molecular BioSystems. 11 (11). Pubs.rsc.org: 2900–2906. doi:10.1039/C5MB00312A. PMID 26252576. Retrieved 23 February 2020.
  64. ^ Wadhwa, Somin; Gupta, Aishwarya; Dokania, Shubham; Kanji, Rakesh; Bagler, Ganesh (2018). "A hierarchical anatomical classification schema for prediction of phenotypic side effects". PLOS ONE. 13 (3): e0193959. Bibcode:2018PLoSO..1393959W. doi:10.1371/journal.pone.0193959. PMC 5832387. PMID 29494708.
  65. ^ Yadav, Reena; Ghatge, Mayur; Hiremath, Kirankumar; Bagler, Ganesh (2015). "Numerical study of variable lung ventilation strategies". arXiv:1509.05163 [q-bio.QM].
  66. ^ Vijay, Vivek; Yadav, Sandeep Kumar; Adhikari, Bibhas; Seshadri, Harinipriya; Fulwani, Deepak Kumar (5 January 2015). Systems Thinking Approach for Social Problems: Proceedings of 37th National Systems Conference, December 2013. Springer. ISBN 9788132221418.
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