The General Obligado Department (in Spanish, Departamento General Obligado) is an administrative subdivision (departamento) of the province of Santa Fe, Argentina. It is located in the northeast of the province. It has about 166,000 inhabitants as per the 2001 census [INDEC]. Its head town is the city of Reconquista (population 66,000).

General Obligado Department
Department
Location of General Obligado Department within Santa Fe Province
Coordinates: 29°40′S 59°12′W / 29.667°S 59.200°W / -29.667; -59.200
Country	Argentina
Province	Santa Fe
Head town	Reconquista
Area
• Total	10,928 km2 (4,219 sq mi)
Population
• Total	166,436
• Density	15/km2 (39/sq mi)
Time zone	UTC-3 (ART)

The department is located on the northeastern "corner" of Santa Fe, bordered by the Vera Department in the west and the San Javier Department in the south. In the north it limits with the province of Chaco, and in the east, with the Paraná River, which is the natural border with the province of Corrientes.

The towns and cities in this department are (in alphabetical order): Arroyo Ceibal, Avellaneda, Berna, El Arazá, El Rabón, El Sombrerito, Florencia, Guadalupe Norte, Ingeniero Chanourdie, Hardy, La Sarita, Lanteri, Las Garzas, Las Toscas, Los Laureles, Malabrigo, Nicanor E. Molinas, Reconquista, San Antonio de Obligado, Tacuarendí, Villa Ana, Villa Guillermina, Villa Ocampo.