George Christopher may refer to:

• George Christopher (mayor) (1907–2000), Greek-American politician, mayor of San Francisco, 1956–1964
• George Christopher (actor) (born 1970), British actor
• George Christopher Molesworth Birdwood (1832–1917), Anglo-Indian official and writer
• George H. Christopher (1888–1959), American Democratic politician from Missouri
• George Christopher, a character on the TV series Bored to Death