The original station was built in 1854 as a stop on the Great Western Railway. Two years later the log structure was replaced (1856) and then again in 1900 by the Wabash-Grand Trunk Railway due to demands on the busy station.

The 1904, the sixth and present station was built using Queen Anne Revival architecture.

The Glencoe Station has been restored to pristine condition. Inside the building is a metal ceiling with pine trim. The ladies waiting room is on the east end with the men's waiting room on the west end. It was proper in at the time the station was built that single men were required to wait in a separate room from ladies and families. Also in the west end was the baggage facilities with the station master's office located in the centre.^[1]

In 2010, the Glencoe Railway Station was inducted into the North America Railway Hall of Fame in the category of "Facilities and Structures: National" for having made significant contributions or achievements relating to the railway industry.

• Glencoe Railway Station
• North America Railway Hall of Fame: Induction Page