Glycine/sarcosine/dimethylglycine N-methyltransferase (EC 2.1.1.162, GSDMT, glycine sarcosine dimethylglycine N-methyltransferase) is an enzyme with systematic name S-adenosyl-L-methionine:glycine(or sarcosine or N,N-dimethylglycine) N-methyltransferase (sarcosine(or N,N-dimethylglycine or betaine)-forming).[1] This enzyme catalyses the following chemical reaction
Glycine/sarcosine/dimethylglycine N-methyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.1.1.162 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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This enzyme from the halophilic methanoarchaeon Methanohalophilus portucalensis can methylate glycine and all of its intermediates to form the compatible solute trimethylglycine.