Originally called the New Grand Opera House and Cirque, it was renamed the Palace of Varieties in 1904, changing its name to the Grand Opera House in 1909. Charlie Chaplin performed there in 1908, and although Variety programmes dominated the pre-war years, entertainers as diverse as Nellie Melba, Sarah Bernhardt, Ralph Richardson and  Gracie Fields performed there regularly. It became a repertory theatre during World War II and at the celebrations to mark the end of the war, Eisenhower, Montgomery and Alanbrooke attended gala performances at the theatre. Lena Horne performed here in the 1940s on her way to and from her travels to France.

After the war, stars of stage and screen returned to the theatre, with notably highlights including performances by Laurel and Hardy, Vera Lynn, Orson Welles, and Luciano Pavarotti in his UK debut. In 1965 the National Theatre brought its production of Love for Love to the Grand Opera House with a cast boasting Laurence Olivier, Lyn Redgrave, Albert Finney, Geraldine McEwan and a young Anthony Hopkins.

The Grand Opera House was acquired by the Rank Organisation, which led to its use as a cinema between 1961 and 1972.

As business slowed in the early 1970s with the onset of the Troubles, Rank initiated plans to sell the theatre to a property developer, who proposed that the building be pulled down and replaced with an office block. However, following the action of Kenneth Jamison (director of the Arts Council of Northern Ireland) and Charles Brett (founder member of the Ulster Architectural Heritage Society and ACNI board member), the building was bought by the Arts Council of Northern Ireland and listed in 1974. The Permanent Secretary of the Department of Education, Arthur Brooke, lent his support to the project and his department provided the funding for extensive renovatation of the theatre. The Grand Opera House reopened in 1980, and in the years that followed many leading performers appeared on its stage, including Liam Neeson, Rowan Atkinson, Kenneth Branagh, Emma Thompson, Ian McKellen, Darcey Bussell and Lesley Garrett.The building has been damaged by bombs on several occasions, usually when the nearby Europa Hotel had been targeted. It was badly damaged by bomb blasts in 1991 and 1993. The theatre continued, however, to host musicals, plays, pantomimes and live music.

2006 renovation and reopening edit

In 1995 the running of the theatre was taken over by the Grand Opera House Trust. In 2006 an extension was added which included a studio theatre space, extended foyers, dressings rooms and access for customers with disabilities. The theatre reopened with a Gala event on 21 October 2006.

Restoration 2020 edit

In 2020 the Grand Opera House closed for restoration and development. The project saw the auditorium's paintings and decorative and ornate plasterwork painstakingly restored and conserved, as well as new seating, carpets, curtains and drapes installed. The design of the foyer and public spaces was reimagined, with a new bar installed in the restored 1980 glass extension overhanging Great Victoria Street, and the stalls and circle bars refurbished. As part of the project, the theatre's technical infrastructure was also upgraded and a permanent heritage exhibition installed telling the theatre's 125-year history installed.

• Grand Opera House website