Grayson Glades Natural Area Preserve is a 53-acre (21 ha) Natural Area Preserve located in Grayson County, Virginia. Its centerpiece is an extremely rare wetland type known as a "mafic fen", which are situated upon soils rich in magnesium and fed by springs. The site is at the headwaters of a small stream system supporting additional mafic fens.^[2]

Grayson Glades Natural Area Preserve
Location	Grayson County, Virginia
Coordinates	36°35′10″N 80°54′28″W / 36.58619°N 80.90779°W / 36.58619; -80.90779[1]
Area	53 acres (21 ha)
Governing body	Virginia Department of Conservation and Recreation

Among the rare species found on the property are tuberous grass-pink (Calopogon tuberosus), ten-angled pipewort (Eriocaulon decangulare var. decangulare), large-leaved grass-of-parnassus (Parnassia grandifolia), queen-of-the-prairie (Filipendula rubra), sticky false-asphodel (Triantha glutinosa) and Canada burnet (Sanguisorba canadensis).^[2]

The preserve is owned and maintained by the Virginia Department of Conservation and Recreation. It does not include improvements for public access, and visitors must make arrangements with a state-employed land steward prior to visiting.^[2]