Gustave Van de Woestijne (Dutch: [vɑn də ʋuˈstɛinə]; 2 August 1881 – 21 April 1947) was a Belgian expressionist painter.

He belonged to the so-called "First Group of Latem", a group of artists who worked in the rural village of Sint-Martens-Latem on the banks of the Lys, near Ghent. He was the brother of the Flemish poet Karel Van de Woestijne. He was buried in the Cemetery of Campo Santo.