Histone H2A-Bbd type 2/3 also known as H2A Barr body-deficient is a histone protein that in humans is encoded by the H2AFB2 gene (H2A histone family, member B1).[5]
H2AB2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | H2AB2, H2A.Bbd, H2A histone family member B2, H2A.B variant histone 2, H2AFB2, H2AB3, H2A.B.1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | MGI: 3644875 HomoloGene: 129517 GeneCards: H2AB2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the middle copy.[5]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.