Histone H3.2 is a protein that in humans is encoded by the HIST2H3C gene.[4][5][6]
H3C14 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | H3C14, H3, H3.2, H3/M, H3F2, H3FM, H3FN, histone cluster 2, H3c, histone cluster 2 H3 family member c, HIST2H3C, H3 clustered histone 14, H3C15, H3C13 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 142780 MGI: 3650546 HomoloGene: 134475 GeneCards: H3C14 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the telomeric copy.[6]