Henry V, Duke of Mecklenburg, nicknamed the Peaceful (3 May 1479 – 6 February 1552), was the reigning Duke of Mecklenburg in the region Mecklenburg-Schwerin, the son of Duke Magnus II and Sophie of Pomerania-Stettin.

Henry V of Mecklenburg
Henry V of Mecklenburg
Born	3 May 1479
Died	6 February 1552(1552-02-06) (aged 72) Schwerin
Spouse	Ursula of Brandenburg Helen of the Palatinate Ursula of Saxe-Lauenburg
House	House of Mecklenburg
Father	Magnus II
Mother	Sophie of Pomerania-Stettin

Henry ruled jointly with his brothers Eric II and Albert VII and his uncle Balthasar from 27 December 1503. Balthasar died on 16 March 1507 and Eric on 22 December 1508, both without an heir, thus Henry and Albert came into possession of the whole country. They ruled jointly at first. Albert repeatedly advocated the division of the territories of Mecklenburg, and this was agreed to in the House Treaty of Neubrandenburg, sealed on 7 May 1520. The treaty stipulated that Henry rule in Schwerin and Albert in Güstrow, without a de facto division of the country.

It was during the reign of the brothers Henry and Albert that Martin Luther launched the Reformation, which quickly found supporters in Mecklenburg. Lutheran doctrine was preached there more or less openly as early as 1523 and perhaps even earlier. Duke Henry supported the new doctrine from the beginning, at first in a very cautious manner, and but more openly after the Diet of Augsburg in 1530. He corresponded with Luther beginning in 1524, and Luther sent him teachers and preachers.

Henry joined the League of Torgau on 12 June 1526, and in 1532 he finally came out publicly as a supporter of Luther. Naturally, his position led him to give the new doctrine a firm external and internal organization, so he asked Superintendent Johann Riebling, whom Luther had recommended to him in 1537, to draft a Church Order, a Catechism and an Agenda. For the remainder of his reign, he was occupied with the organization of the Lutheran church.

After Luther's death, a religious war erupted in Germany. Henry, however, did not participate; although he was a Protestant prince, he was not a member of the Schmalkaldic League. He resisted the introduction of the Augsburg Interim by Emperor Charles V in 1548. Henry approved the decision of the Mecklenburg estates of July 1549 that formally recognized by the Lutheran doctrine. Soon after, on 6 February 1552, he died with the reputation of a pious and peaceable prince.