He was the son of biology professor at the Theological-Philosophical College at Dillingen, where he grew up. He studied under Hermann Merxmüller in Munich and completed a thesis there on Ceropegia in 1958. After graduating he took up a position as curator at the Botanic Garden at the University of Würzburg, and from there he became professor of botany at the University of Mérida, Venezuela. On returning to Germany he became chair of the Hamburg Herbarium, before taking up the position at Kaiserslautern where he remained till retirement.^[2]

Huber was one of the first scientists to challenge the traditional division of angiosperms into monocotyledons and dicotyledons, on morphological grounds. He was also amongst the first taxonomists to suggest that the vast Liliaceae family be broken up into smaller family units. His contributions did not meet a wide audience outside of his own country since he mainly wrote in German, and publishing in the Mitteilungen der Botanischen Staatssammlung München.^[2]

It was at Munich that his most influential paper Die Samenmerkmale und Verwandtschaftsverhältnisse der Liliiflorae (1969)^[3] was written, a detailed study of the seeds of Liliiflorae and in particular the Liliaceae, in which he proposed splitting the family into two, the 'Asparagoid' Liliiflorae and the 'Colchicoid' Lilliiflorae. Huber's narrower conception of families, was an important stepping stone towards the eventual family structure produced by the Angiosperm Phylogeny Group.^[4] When Dahlgren and Clifford published their study of families of monocotyledons (1985)^[5] they developed and popularised Huber's concept, giving rise to the formation of a new order, the Asparagales. Other important work deals with the Rosiflorae (sensu Dahlgren), the classification of dicotyledons and seed anatomy.^[2]

The genus Hubera was named after him.^[6]

• Huber, H. (1955) Ceropegia humbertii Mitt. Bot. Staatssamml. Munchen, Heft 12: 72.
• Huber, H. (1985) Annonaceae, pp. 1–75. In: Dassanayake, M.D. & Fosberg, F.R. (eds.), A revised handbook to the flora of Ceylon, 5. Amerind Publishing Co., New Delhi, 476 pp
• Huber, H (1969). "Die Samenmerkmale und Verwandtschaftsverhältnisse der Liliiflorae". Mitt. Bot. Staatssamml.[Mitteilungen der Botanischen Staatssammlung München]. 8: 219–538. Retrieved 10 February 2015.
• Huber, H. (1977). "The treatment of monocotyledons in an evolutionary system of classification". In Kubitzki, Klaus (ed.). Flowering plants: Evolution and classification of higher categories. Symposium, Hamburg, September 8–12, 1976. Plant Systematics and Evolution. Vol. Supplementum 1. Wien: Springer. pp. 285–298. doi:10.1007/978-3-7091-7076-2_18. ISBN 978-3-211-81434-5.
• Kubitzki, Klaus; Huber, Herbert, eds. (1998). The families and genera of vascular plants. Vol.3. Berlin, Germany: Springer-Verlag. ISBN 978-3-540-64060-8. Retrieved 14 January 2014.