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INTEGRALL

Summary

Integrall is a database that seeks to document and annotate integrons and all other transposable elements that confer resistance to antibiotics in bacteria.[1]

Integrall
Content
DescriptionDatabase that collects and documents integrons and transposable elements conferring resistance.
Data types
captured		Integrons and other transposable elements
OrganismsBacteria
Contact
Primary citationPMID 19228805
Access
Websiteintegrall.bio.ua.pt
Miscellaneous
Bookmarkable
entities		yes

As of release 1.2, Integrall contains ~4800 integron sequences.[1] Transposable elements and Integrons in bacteria are a major threat in the field of antimicrobial drug research because they allow bacteria to develop resistances through interbacterial interactions.[2][3] They allow bacteria to develop resistances that they typically cannot.[3] Thus, Integrall seeks to be a comprehensive and unified database that facilitates the understanding and usage of integron information. Integrall is built on PHP5 using MySQL 5.0.

See also edit

References edit

  1. ^ a b Moura, A.; Soares, M.; Pereira, C.; Leitao, N.; Henriques, I.; Correia, A. (2009-04-15). "INTEGRALL: a database and search engine for integrons, integrases and gene cassettes". Bioinformatics. 25 (8): 1096–1098. doi:10.1093/bioinformatics/btp105. ISSN 1367-4803. PMID 19228805. S2CID 15350885.
  2. ^ Sørensen, Søren J.; Bailey, Mark; Hansen, Lars H.; Kroer, Niels; Wuertz, Stefan (September 2005). "Studying plasmid horizontal transfer in situ: a critical review". Nature Reviews Microbiology. 3 (9): 700–710. doi:10.1038/nrmicro1232. ISSN 1740-1526. PMID 16138098. S2CID 39068141.
  3. ^ a b Hentschel, Ute; Hacker, Jörg (June 2001). "Pathogenicity islands: the tip of the iceberg". Microbes and Infection. 3 (7): 545–548. doi:10.1016/s1286-4579(01)01410-1. ISSN 1286-4579. PMID 11418328.