Imidazopyridine

Summary

An imidazopyridine is a nitrogen containing heterocycle that is also a class of drugs that contain this same chemical substructure. In general, they are GABAA receptor agonists, however recently proton pump inhibitors, aromatase inhibitors, NSAIDs and other classes of drugs in this class have been developed as well. Despite usually being similar to them in effect, they are not chemically related to benzodiazepines. As such, GABAA-agonizing imidazopyridines, pyrazolopyrimidines, and cyclopyrrones are sometimes grouped together and referred to as "nonbenzodiazepines." Imidazopyridines include:

Imidazo[1,2-a]pyridine—an example of imidazopyridine and a core structure of zolpidem and some compounds described below.
Imidazo[1,2-a]pyridine—an example of imidazopyridine and a core structure of zolpidem and some compounds described below.

Sedatives edit

Anxiolytics, sedatives and hypnotics (GABAA receptor positive allosteric modulators):

Antipsychotic edit

Antipsychotics:

Gastrointestinal edit

Drugs used for peptic ulcer disease (PUD), GERD and gastroprokinetic agents (motility stimulants):

Anti-inflammatories edit

NSAIDs, analgesics and antimigraine drugs:

Cardiovascular edit

Drugs acting on the cardiovascular system:

Bone edit

Drugs for treatment of bone diseases:

Antineoplastic edit

Antineoplastic agents:

Antiviral edit

Directly-acting antiviral agents:

DAergic edit

  • PIP3EA [885446-91-3] D4 agonist supported to have penile erectant properties.

References edit

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External links edit

  •   Media related to Imidazopyridines at Wikimedia Commons