• Isön, a small island in lake Storsjön, Jämtland, Sweden

First name / given name edit

• Ison (rapper), stage name of Ison Glasgow, a Swedish rapper of American origin

Last name / family name edit

• David Ison, Anglican clergyman
• Hobart Ison, American businessman
• Paul E. Ison (1916–2001), American Marine during World War II
• Sheila Ison (1944–2002), American political activist
• Tara Ison, American novelist
• Wayne Ison (1924–2014), American aircraft designer

• ISON Airbike
• Ison miniMAX
• Ison Hi-MAX

• Ison (music), a drone note of Byzantine chant
• ISON (album), 2017 debut album by Iranian-Dutch singer Sevdaliza
• Mega Ison, a method of religious chant composition

• Ison, a muscadine (Vitis rotundifolia) cultivar
• ISON, an IRC command to see whether a nick is currently online

• International Scientific Optical Network or ISON
• Comet ISON, a disintegrated sungrazing comet

• Ison Creek Kimberlite