The college was started in 1951 and it was affiliated to University of Madras. Later, Since 1982 it is affiliated to Bharathidasan University.^[1] The college is administered by the Society of Jamal Mohamed College. It is established in a sprawling land area of 87 acres, as a religious minority institution. Janab M. Jamal Mohamed Sahib and Janab N.M. Khajamian Rowther were the founding fathers of this institution.

In 1963 the college was elevated to the status of a post-graduate college.

In the year 1972, the college was recognized by UGC New Delhi, for the purposes of Grants under section 2(F) and 12(B) of the University Grants Commission Act 1956. In 1977, on the recommendation of the University of Madras, the UGC recognized the college as one of the ten "Lead colleges" in the university area.

The college was accredited at Five Star Level by NAAC during 2002 and conferred with Autonomous Status by UGC, New Delhi and Bharathidasan University in 2004–2005. In January 2009, the college was accredited by NAAC with A-Grade (2nd Cycle) - CGPA 3.6 out of 4.0. Our College was bestowed with the unique honour of "CPE" status Phase-I and Phase-II by the University Grants Commission under the Scheme "Colleges with Potential for Excellence" in 2011 and 2016 respectively. We retained the ‘A’ Grade awarded by NAAC during the third cycle of accreditation in 2015.

The college is moving ahead with a sporting spirit by securing prestigious top rankings in the NIRF Assessment for the Higher Educational Institutions in India. The college has raised its status from 59th to 54thrank in the NIRF Ranking 2020. It is remarkable to state that the college has been recognized with Three Star status by the Institutions Innovation Council (IIC), MHRD innovation cell, Government of India in 2019. Department of Science and Technology (DST), Government of India has accorded FIST Scheme to the Departments of Zoology, Botany and Physics in 2004 and to the Department of Mathematics in 2008. Again DST FIST Scheme has been extended to the Departments of Mathematics, Physics, Chemistry, Botany, Zoology and Computer Science in 2019. Five Science Departments viz. Mathematics, Physics, Chemistry, Botany and Zoology have been awarded the Star College Scheme by the Department of Bio Technology (DBT) in 2020.

Over a period of 70 years the college was able to raise to the present status as a multi-faculty institution with 23 UG and 20 PG programmes. 19 departments of the college are functioning with the status of approved research centres. The college has a strength of around 12,000 students. There are 145 Government Aided teaching faculty and 354 staff members are working under the self-finance stream. The college celebrated its silver Jubilee in 1971, subsequently the Golden Jubilee and Diamond Jubilee in 2001 and 2011 respectively. ^[1]

The college was able to become a multi-faculty institution with 11 UG programmes, 11 PG programmes and 2 M.Phil. Programmes under Government Aided stream and 11 U.G. programmes, 13 P.G. programmes, 17 M.Phil. and 16 Ph.D. programmes under self financing stream for men by promoting quality and excellence in higher education due to the sustained efforts and dedicated leadership given by the College Management Committee. The college also offers 13 U.G., 14 P.G. programmes, 16 M.Phil. and 15 Ph.D. programmes exclusively for women as part of women empowerment during the second shift of the college. During 2021–22, the college offers 23 Under Graduate, 20 Post Graduate, 7 UGC Sponsored Career-Oriented programmes, 17 M.Phil. and 16 Ph.D., programmes. The present student strength is around 12,000, of which 4605 are women students. There are about 494 Teaching and 297 Non-teaching staff.

The college celebrated its silver Jubilee in 1971, subsequently the Golden Jubilee and Diamond Jubilee in 2001 and 2011 respectively.

• 1976 Silver Jubilee Celebrated.
• 2001 Golden Jubilee Celebrated.
• 2011 Diamond Jubilee Valedictory function on 07.02.2011 on completion of 60 Years with a student strength of 9625.

• 1951 College – Inaugurated with Intermediate and UG Courses - Affiliated to University of Madras
• 1960 Khajamian Men’s Hostel - Inaugurated.
• 1963 PG Courses – Started.
• 1963 Alumni Association – Formed.
• 1972 UGC Recognized under 2(f) and 12 (B) of UGC act 1956
• 1974 Ph.D Research Programme – Commenced.
• 1976 UGC Recognized the College as one of the Ten "Lead Colleges" in the state.
• 1976 Silver Jubilee Celebrated.
• 1982 Affiliated to Bharathidasan University.
• 1983 M.Phil Courses – Started.
• 1985 PG Self-Finance Courses – Started.
• 1986 UG Computer Science Course – Started.
• 1987 PG Diploma Courses – Started.
• 1988 AICTE approved M.C.A – Started.
• 1990 University of Madras – Institute of Correspondence Education – Spot Admission Centre – Stared.
• 1991 Alumni Association Overseas Chapter – Inaugurated.
• 1995 UG Self-Finance Courses-Men – Started.
• 1997 Inauguration of Alumni Chapter, Jeddah
• 1997 Inauguration of Alumni Chapter, UAE
• 1999 UG Self-Finance Courses-women – Started shift II.
• 1999 Inauguration of Alumni Chapter, Malaysia
• 1999 Inauguration of Alumni Chapter, Singapore
• 1999 Inauguration of Alumni Chapter, Kuwait
• 2000 AICTE approved M.B.A – Started.
• 2001 Golden Jubilee Celebrated.
• 2001 Computerized Calligraphy Training Centre Approved by National Council for promoting Urdu language (Ministry of HRD, New Delhi) - Started
• 2002 Accredited by NAAC at Five Star Level.
• 2003 PG Self-Finance Courses-Women – Started shift II
• 2004 Autonomous Status – Conferred.
• 2005 Women Hostel – Inaugurated.
• 2005 UGC Approved Six Carrier Oriented Programmes (COP) - Started
• 2007 PG Self-Finance Courses Women - started Shift I
• 2007 Five years Ulama Course with B.A (Arabic) and M.A (Arabic) – Started
• 2007 Anna University, Chennai Study Centres – Distance Education – Started.
• 2008 Convergence Scheme with IGNOU and Twinning Programme with Pondicherry University - Started.
• 2008 Department of Technical Education approved Type Writing Institute - Started
• 2008 Received Permanent Affiliation orders for Govt. Aided 11 UG, 11 PG and 2 M.Phil Courses
• 2008 13 UG & 15 PG Additional Sections Started
• 2009 Accredited by NAAC at ‘A’ Grade (CGPA 3.6 out of 4.0)
• 2009 3 UG & 1 PG Additional sections started
• 2009 MBA second section started with AICTE Approval
• 2009 Ph.D in Computer Science and Management Studies started
• 2009 Received Permanent Affiliation orders for Self Finance MA (English), M.Com, MBA, MCA, M.Sc(IT), M.Sc(CS), BA (English- 2 sections), B.Com(4-sections),B.Sc., Mathematics, 13 M.Phil, 12 Ph.D and 7 Carrier Oriented Programmes (COP).
• 2010 Additional Section in M.A., English, M.Sc., Mathematics for Men, 4 Year B.S., Biotechnology and additional section in B.Sc., I.T for Women, PG Diploma in Fermentation Technology and UGC approved COP course in E-Mathematical Tools.
• 2010 Diamond Jubilee Inaugural Function on 11.07.2010
• 2010 Received Permanent Affiliation orders for 2 sections of M.Sc., Biotechnology
• 2010 Extension of Autonomous status for 6 more years conferred by UGC and Bharathidasan University
• 2010 Singapore Alumni Chapter register as Society
• 2011 Received Permanent Affiliation orders for M.B.A., Additional section-I and M.Sc., Chemistry (2 sections)
• 2011 Declared open Diamond Jubilee arch
• 2011 Diamond Jubilee Valedictory function on 07.02.2011 on completion of 60 Years with a students strength of 9625.
• 2011 Awarded “College with Potential for Excellence Status” with a financial grant of Rs. 1.5 Crores by the UGC, New Delhi
• 2011 Awarded Accreditation for 3 Years for M.B.A., Programme by National Board of Accreditation of AICTE, New Delhi.
• 2012 B.Sc., Biotechnology, M.Phil and Ph.D in Biotechnology and Microbiology, Ph.D in Physical Education, Advanced Diploma in Computer Applications with Arabic courses were started.
• 2012 Inauguration of the Indoor Stadium constructed with partial UGC funding.
• 2013 PG Diploma in Bio Diversity Informatics under UGC Sponsored innovative scheme was introduced.
• 2013 College is identified by the Ministry of Human Resource Development (MHRD) as one of the 45 Colleges in India to be accorded the power to grant degrees in the status of a state University.
• 2014 Jamal Institute of Management has been Ranked in Category ‘A’ by the All India Management Association (AIMA), New Delhi, Business Standard B-Schools Ratings.
• 2014 Additional Section in B.Sc., Hotel Management and Catering Science for Men and B.Sc., Physics for Women were started.
• 2015 B.Com additional section (VIII) for men introduced
• 2015 B.Sc. Microbiology section started for Women Section
• 2015 B.Sc. Mathematics additional section (III) fro Women Started
• 2016 Visit of UGC expert committee to evaluate the performance and academic attainment and to recommend the extension Autonomous status of 6 more years (upto 2021 - 2022)
• 2016 Visist of the National Assessment and Accreditation Council (NAAC) Peer Team for Re-accreditation (3rd Cycle) process.
• 2016 The UGC has granted extension of Autonomous status for the further period of six years from 2016-17 to 2021-2022
• 2016 The College is Re-accredited by NAAC in the Third Cycle with 'A' Grade
• 2016 B.C.A. additional section (VII) for men introduced
• 2016 B.Com. additional section (IX) for women introduced
• 2016 B.Sc. Visual Communication for men started
• 2016 Inauguration of Alumni Chapter, Tiruchirappalli
• College was bestowed with the unique honour of 'CPE' status (Phase-II) by the University Grants Commission in 2016-2017
• During the year 2016 - 2017, Ph. D. programme in History was introduced.
• The syllabi for UG, PG, M. Phil and other programmes were revised during the year 2016 - 2017 for implementations from the academic year 2017 - 2018
• During 2017-18, M.Phil., Nutrition and Dietetics Course was started. A Centre for Islamic Cultural Research was also established.
• Our College was ranked as one of the Top hundred colleges (83rd rank) in the National Institutional Ranking Framework in 2017-18 by MHRD, New Delhi.
• The Conferement of Muslim Minority Status was given by the Government of Tamil Nadu for the period of five years from 2017-18 to 2021-22.
• During the academic year 2018-19, B.A. Arabic and B.Sc., Zoology for women and M.Phil., Social Work Programmes were started. The Affiliation was also granted for UGC sponsored B.Voc., Food Processing and Safety and B.Voc., Apparel and Fashion Design programme under NSQF.
• During 2018-19, Innovation and Incubation Centre and Intellectual Property Rights Cell were established.
• Our College was ranked as one of the Top hundred Colleges (59th rank) in the National Institutional Ranking Framework in 2018-19 by MHRD, New Delhi.
• The Department of Visual Communication took initiative to release a News Letter-Jamal Insider in 2018-19.
• The government of Tamil Nadu identified our College to sanction infrastructure grants under RUSA Scheme.
• DST sort listed our College to sanction FIST Level “O” grant under the PG Colleges for College as a whole
• Under Unnat Bharat Abhiyan Scheme (from IIT, Delhi), our College was granted permission to transform local communities through participating envisioning sustainable growth, healthy practices among the public and private sectors to make better India.
• DST sanctioned FIST Level "O" grant of Rs. 1,10,00,000/- (Rupees One Crore and ten lakhs) for a period of 5 years to support financially 6 Departments of our College namely Mathematics, Physics, Chemistry, Botany, Zoology and Computer Science in 2020.
• Thiru Edappadi K. Palaniswami, Honble Chief Minister of Tamil Nadu, presented The New Indian Express "Think Edu Award" to our College on 9th January 2020 for our consistent efforts in providing quality education.
• Five Science Departments such as Mathematics, Physics, Chemistry, Botany and Zoology have been short-listed after a meritorious presentation, among many competing institutions and awarded the Star College Scheme by the Department of Bio-Technology (DBT) in 2020.
• During the academic year 2020-2021, Our College was ranked as one of the Top hundred Colleges (65th rank) in the National Institutional Ranking Framework -2021 by MHRD, New Delhi.
• The syllabus was revised with the introduction of Outcome Based Education for all UG, PG and M.Phil Programmes to be implemented from the academic year 2020-2021.
• B.Voc Tourism and Hospitality Management and B.Voc Media Production were started during the academic year 2020-2021. Besides, Diploma programmes in Aquaculture, Horticulture and Insurance and Actuarial Science were also started for men students in this same academic year 2020-21 under UGC NSQF Scheme.
• JMC Alumni Association Chapters were formed in UK, USA, Tenkasi, Kongunadu and were inaugurated through online in the academic year 2020-2021.
• Global Alumni Job Search Engine exclusively for Jamalians was created with the support of the alumni spread all over the globe during the academic year 2020-2021.
• Our college has secured 79th position in the National Institutional Ranking Framework (NIRF) 2022.