Jeremiah Langhorne (died 1742) was a prominent landowner and jurist in colonial Pennsylvania. He is the namesake of present-day Langhorne, Pennsylvania,^[1] which adopted his name in 1876, and neighboring Langhorne Manor.

A Quaker, Langhorne settled with his family in Bucks County in 1684. Records show that he purchased 7,200 acres (29 km²) there in 1724. He represented Bucks County in the Pennsylvania Provincial Assembly, of which he served twice as Speaker. He was a justice of the Pennsylvania Supreme Court from 1726, and served as chief justice from 1739 until his death in 1742.