John Wiley may refer to:

• John Wiley & Sons, a publishing company
• John A. Wiley (1843–1909), Pennsylvania businessman, National Guard and Civil War soldier
• John Cooper Wiley (1893–1967), US foreign service officer and ambassador
• John D. Wiley (born 1942), former Chancellor of the University of Wisconsin–Madison
• John F. Wiley (1920–2013), American football player and coach
• John M. Wiley (1841–1912), U.S. Representative from New York
• John Wiley Bryant (born 1947), Texas politician
• John Wiley (politician) (1927–1987), South African cricketer and politician