Julian John Thurstan Gough (born 1974)[2] is a Group Leader in the Laboratory of Molecular Biology (LMB) of the Medical Research Council (MRC).[1][7][8] He was previously[when?] a professor of bioinformatics at the University of Bristol.[9]
Julian Gough | |
---|---|
Born | Julian John Thurstan Gough[6] September 1974 (age 49)[2] |
Education | The Perse School |
Alma mater |
|
Known for | Superfamily database |
Scientific career | |
Fields | |
Institutions |
|
Thesis | Hidden Markov models and their application to the genome analysis in the context of protein structure (2001) |
Doctoral advisor | Cyrus Chothia[4][5] |
Website | www2 |
Gough was educated at The Perse School[10] in Cambridge and the University of Bristol where he was awarded a joint honours degree in Mathematics and Physics in 1998.[9][10] He went on to complete his PhD in the Laboratory of Molecular Biology (LMB) supervised by Cyrus Chothia on genome analysis and protein structure as a postgraduate student of Sidney Sussex College, Cambridge, graduating in 2001.[5]
Following his PhD, Gough completed postdoctoral research at the LMB and Stanford University, with Michael Levitt. Subsequently, he was a scientist at RIKEN in Tokyo before being appointed a member of faculty at the University of Bristol, where he has worked since 2007.[10] He has also been a visiting scientist at the Pasteur Institute in Paris and an associate professor at Tokyo Medical and Dental University.[9]
Gough's research interests are in bioinformatics, computational biology, molecular biology, genomics[1] which has led to the creation of the Superfamily database[11][12] of Hidden Markov models (HMMs) representing all proteins of known structure. His research has been published in leading peer reviewed scientific journals including Nature,[13][14] Science,[15][16] Cell,[17] Nucleic Acids Research,[18][19][20][21][22] PNAS,[23][24] the Biochemical Journal,[25] the Journal of Molecular Biology,[26][27][28] Genome Research,[29] Bioinformatics,[30] PLOS Genetics,[31] Nature Genetics[32] and the Journal of Bacteriology.[33]
Gough's research has been funded by the Biotechnology and Biological Sciences Research Council (BBSRC), the Engineering and Physical Sciences Research Council (EPSRC), the Natural Environment Research Council (NERC),[34] the European Union (EU) Seventh Research Framework Programme (FP7), the Japan Society for the Promotion of Science (JSPS) and the Royal Society of London.[9]