KIF5C Knowpia

KIF5C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1VFV, 1VFW, 1VFX, 1VFZ, 3J6H, 3WRD, 3X2T
Identifiers
Aliases	KIF5C, CDCBM2, KINN, NKHC, NKHC-2, NKHC2, kinesin family member 5C
External IDs	OMIM: 604593 MGI: 1098269 HomoloGene: 56234 GeneCards: KIF5C
Gene location (Human)
Chr.	Chromosome 2 (human)
End	149,026,759 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	49,664,790 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; frontal pole; ; cerebellar vermis; ; middle temporal gyrus; ; middle frontal gyrus; ; Brodmann area 46; ; postcentral gyrus; ; Brodmann area 23; ; orbitofrontal cortex; ; endothelial cell;
	Top expressed in
	globus pallidus; ; substantia nigra; ; cerebellar vermis; ; lateral geniculate nucleus; ; facial motor nucleus; ; ventral tegmental area; ; subiculum; ; lateral hypothalamus; ; pontine nuclei; ; medial geniculate nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	microtubule motor activity; nucleotide binding; microtubule binding; protein binding; plus-end-directed microtubule motor activity; ATP binding; ATPase activity;
Cellular component	cytoplasm; kinesin complex; ciliary rootlet; neuron projection; microtubule; cytoskeleton; dendrite; dendrite cytoplasm; cell projection; neuronal cell body; axonal growth cone; synapse; distal axon; axon cytoplasm;
Biological process	protein localization; cytoskeleton-dependent intracellular transport; mRNA transport; organelle organization; axon guidance; microtubule-based movement; motor neuron axon guidance; synaptic vesicle transport; anterograde dendritic transport of neurotransmitter receptor complex; anterograde axonal protein transport;
	Sources:Amigo / QuickGO
Orthologs
	3800
	16574
	ENSG00000168280; ENSG00000276734
	ENSMUSG00000026764
	O60282
	P28738
	NM_004522
	NM_008449
	NP_004513
	NP_032475
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin heavy chain isoform 5C is a protein that in humans is encoded by the KIF5C gene.^[5]^[6] It is part of the kinesin family of motor proteins.

References edit

^ ^a ^b ^c ENSG00000276734 GRCh38: Ensembl release 89: ENSG00000168280, ENSG00000276734 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000026764 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Niclas J, Navone F, Hom-Booher N, Vale RD (Jun 1994). "Cloning and localization of a conventional kinesin motor expressed exclusively in neurons". Neuron. 12 (5): 1059–72. doi:10.1016/0896-6273(94)90314-X. PMID 7514426. S2CID 32927183.
^ "Entrez Gene: KIF5C kinesin family member 5C".