KLF may refer to:

• The KLF, a band
• Karachi Literature Festival, held annually in Pakistan
• Kerala Literature Festival, held annually in India
• Kosmic Loader Foundation, later Kosmic Free Music Foundation, a netlabel
• Krüppel-like factors, proteins regulating gene expression
• Radio KLF, Finland
• Khalistan Liberation Force, Khalistani separatist militant organization
• Kaluga Airport IATA code
• Kunlun Fight, a Chinese kickboxing promotion