KRT80 Knowpia

KRT80
Identifiers
Aliases	KRT80, KB20, keratin 80
External IDs	OMIM: 611161 MGI: 1921377 HomoloGene: 66610 GeneCards: KRT80
Gene location (Human)
Chr.	Chromosome 12 (human)
End	52,192,014 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	101,268,043 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; amniotic fluid; ; gums; ; vulva; ; human penis; ; oral cavity; ; islet of Langerhans; ; palpebral conjunctiva; ; parotid gland; ; minor salivary glands;
	Top expressed in
	lip; ; esophagus; ; skin of back; ; right lung; ; right lung lobe; ; molar; ; conjunctival fornix; ; cornea; ; belly cord; ; left lung;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; structural molecule activity;
Cellular component	cytoplasm; desmosome; keratin filament; intermediate filament; cytosol; intermediate filament cytoskeleton;
Biological process	keratinization; cornification;
	Sources:Amigo / QuickGO
Orthologs
	144501
	74127
	ENSG00000167767
	ENSMUSG00000037185
	Q6KB66
	Q0VBK2
	NM_001081492; NM_182507
	NM_028770
	NP_001074961; NP_872313
	NP_083046
	Wikidata
View/Edit Human	View/Edit Mouse

Keratin 80, also known as KRT80, is a protein which humans is encoded by the KRT80 gene.^[5]^[6]

Function edit

Keratins, such as KRT80, are filament proteins that make up one of the major structural fibers of epithelial cells.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167767 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000037185 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (July 2006). "New consensus nomenclature for mammalian keratins". J. Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
^ "Entrez Gene: KRT80 keratin 80".
^ Rogers MA, Edler L, Winter H, Langbein L, Beckmann I, Schweizer J (March 2005). "Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13". J. Invest. Dermatol. 124 (3): 536–44. doi:10.1111/j.0022-202X.2004.23530.x. PMID 15737194.