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Kebuzone

Summary

Kebuzone (or ketophenylbutazone) is a nonsteroidal anti-inflammatory drug (NSAID) that is used for the treatment of inflammatory conditions such as thrombophlebitis and rheumatoid arthritis (RA).[1][2][3]

Kebuzone
Clinical data
Routes of
administration		intramuscular
ATC code
Pharmacokinetic data
Elimination half-life70–100 hours
Excretionrenal
Identifiers
  • 4-(3-oxobutyl)-1,2-di(phenyl)pyrazolidine-3,5-dione
CAS Number
  • 853-34-9 checkY
PubChem CID
  • 3824
DrugBank
  • DB08940 ☒N
ChemSpider
  • 3692 ☒N
UNII
  • 4VD83UL6Y6
KEGG
  • D01567 checkY
ChEBI
  • CHEBI:31749 ☒N
CompTox Dashboard (EPA)
  • DTXSID00234500 Edit this at Wikidata
ECHA InfoCard100.011.560 Edit this at Wikidata
Chemical and physical data
FormulaC19H18N2O3
Molar mass322.364 g·mol−1
3D model (JSmol)
  • Interactive image
  • CC(=O)CCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3
  • InChI=1S/C19H18N2O3/c1-14(22)12-13-17-18(23)20(15-8-4-2-5-9-15)21(19(17)24)16-10-6-3-7-11-16/h2-11,17H,12-13H2,1H3 ☒N
  • Key:LGYTZKPVOAIUKX-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

References edit

  1. ^ Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. 2018. Rheumesser 3 ml-Ampullen.
  2. ^ "KEBUZONE". NCATS Inxight: Drugs. Retrieved 2019-02-27.
  3. ^ Aronson JK (2016). "Kebuzone". Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions (Sixteenth ed.). Amsterdam. p. 405. ISBN 978-0-444-53716-4.{{cite book}}: CS1 maint: location missing publisher (link)