Khnumhotep (alt. Khnumhotpe, Khnemhotpe) is an ancient Egyptian personal theophoric name which may refer to:

• Khnumhotep, an Overseer of the Manicurists under pharaoh Nyuserre (5th Dynasty), famous for his tomb shared with Niankhkhnum
• Khnumhotep I, a nomarch under pharaoh Amenemhat I (12th Dynasty)
• Khnumhotep II, a nomarch under pharaoh Amenemhat II and Senusret II (12th Dynasty), and grandson of Khnumhotep I
• Khnumhotep III, a vizier under pharaohs Senusret II and Senusret III (12th Dynasty), and son of Khnumhotep II
• Khnumhotep IV, a nomarch, son and successor of Khnumhotep II and brother of Khnumhotep III

Khnumhotep in hieroglyphs
(Khnum hotep) ẖnmw-ḥtp Khnum is pleased