Knightswood features on maps by Ordnance Survey cartographer William Roy dating back to 1748–55, which show it lying within the parish of New Kilpatrick in Dumbartonshire.^[9][10] The modern area is defined at its northern edge by the Forth and Clyde Canal (beyond which is Bearsden)^[11] which began construction in the 1760s and opened as the Great Canal in 1790.^[12] Drumchapel and Yoker lie to the west, beyond Duntreath Avenue and Yoker Mill Road. At its southern edge, Knightswood is bounded by Anniesland Road, beyond which lies Jordanhill and Scotstoun. Netherton and Temple lie to the east. Both of these settlements (with Jordanhill and Scotstoun) appear on Joan Blaeu's 1662 Atlas of Scotland, but Knightswood is not shown, either omitted or not yet of significance.^[13] The earliest recorded settlement (1740) in the Knightswood area was known as the Red Town, a small village supporting ironstone miners and brickmakers.^{[14][15][16][17][18]}

Just before the First World War, Knightswood consisted of an Infectious Diseases Hospital (founded 1877^[19]) with a line of terraced cottages to the north called Knightswood Rows, a few houses on the site of Knightswood Secondary School (all that remained of Red Town), but the area was otherwise unpopulated farmland and disused mineworkings.^[20][21][15]

Great Western Road was constructed under government patronage^[21] between 1924 and 1927 from Anniesland Cross to Duntocher, north of Clydebank.^[22][23] Much of the housing in the area was constructed in three phases during the 1920s and 1930s on garden suburb principles.^[24][15] This housing was mainly of cottage flat and semi-detached types,^[25][26][27] and is similar to other parts of the city such as Mosspark in the South Side and Carntyne in the East End^[15] and used for the relocation of people from slum tenements cleared near the city centre.^[28][29] Land surrounding the junction of Great Western Road and Knightswood Road was designated for the use of several church denominations,^{[30][31][32][33]} and the nearby Knightswood Park, but there were no designated industrial areas or public houses, which remained in adjacent Temple and Scotstoun/Yoker.

In 1926, the district was brought under the official control of the city of Glasgow,^[34] which had purchased land outside its existing boundary from the Summerlee Iron Company for the building of the estate.^[21] During the Second World War, Knightswood Hospital treated wounded soldiers.^[35]

Knightswood, along with Jordanhill and Temple have been linked to stories of the Knights Templar; but according to the late Lord Lyon King of Arms there is no evidence for their presence in this area. Nevertheless, the theories continue to persist and are sometimes actively encouraged, as in the use of "heraldic" local street names (Archerhill Road, Arrowsmith Avenue, Ivanhoe Road, Minstrel Road, Talisman Road, Templar Avenue, Turret Road) by Glasgow Corporation, even though Knightswood only appears in the records from the 18th century, long after the days of knights.^[36]

Immediately following the war, spare land on the estate was used for temporary housing in the form of prefabs.^[37] These were replaced in the 1960s with high-rise buildings.^[15][38] In 1958, Glasgow Corporation opened a Fire Station^[39] which now houses a specialist water rescue unit.^[40]

Knightswood Hospital gradually lost services to other Glasgow Hospitals from the 1960s onwards, ending up as a Geriatric Unit and finally closing in March 2000.^[41] The hospital site is now the Academy Park residential development. In 2008, Knightswood gained a new church congregation at Knightswood Cross when the Free Church of Scotland (Continuing) moved from temporary premises in Thornwood to the former Brethren Gospel Hall.^[42][43][44]

In the 2010s, concerns were raised that some of the land of Knightswood was liable to flooding in times of extreme rainfall, which had been increasingly common in recent times and was considered likely to continue; in 2019, plans were outlined to have prevention measures put in place.^[45]

• Member of Parliament (Glasgow North West constituency): Carol Monaghan (SNP)
• Member of Scottish Parliament: Currently Bill Kidd of the (SNP); since the 2011 Scottish Parliament election, the area falls into the new constituency of Glasgow Anniesland.^[46]
• Glasgow City Council: whilst
  • Ward 13 Garscadden/Scotstounhill, covers Low Knightswood – the Councillors for this multi member ward as of May 2012 are: Michael Cullen, Bill Butler, Eva Murray and Chris Cunningham.
  • Ward 14 Drumchapel/Anniesland, covers High Knightswood – the Councillors for this multi-member ward as of May 2012 are: Paul Carey, Malcolm Balfour, Elspeth Kerr and Anne McTaggart.

Glasgow City Council run Knightswood Park Gala Day,^[47] an event for council and community groups in the area. It has been held on a Saturday at some time during the summer since 2008. The first event on 12 July 2008 was supported by Glasgow City Council, Strathclyde Fire Brigade, local churches (St David's Church of Scotland^[32] and Knightswood Baptist Church^[30]) and local clubs.^[48][49][50]

The second Gala Day took place on 27 June 2009. The event started with the arrival of the Kingsway carnival parade at midday.^[51] There were demonstrations of falconry and sheepdog trials (herding Indian Runner Ducks due to space restrictions), live music, live entertainment, bouncy castles, stalls promoting community groups and clubs, Baptist church and fire brigade (as 2008). On site catering was provided this year, and first-aid cover was provided by St. Andrew's Ambulance Association.^[52]

In 2010 and 2011, Trinley Brae Allotments took part in the Open Gates event as part of Glasgow's Doors Open Day. This has developed links with the local community and other community events have taken place since the first event in September 2010.^[53][54] Members are currently researching the history of the allotment site and have the worked with the city council on other community events.^[55]

Knightswood caters for its residents with a community centre,^[56] library,^[57] secondary^[58] and primary schools. Knightswood Swimming Pool, opened in 1971, was permanently closed in March 2010.^[59] Construction of Scotland's only Olympic standard BMX racing track was undertaken in Knightswood Park; the facility was used to host the 2018 European Championships, and means that Glasgow is the only city in the world that can host all four Olympic cycling disciplines (BMX, MTB, Road and Track) within its boundaries (the others are the Sir Chris Hoy Velodrome at the Emirates Arena (Track), Cathkin Braes Mountain Bike Trails and the city's streets for road races as used during the 2014 Commonwealth Games).^[60] These facilities were put to use again in the 2023 UCI Cycling World Championships.^[61]

Knightswood Secondary School is also home to the Dance School of Scotland.^[62] Shopping in Knightswood can be done in many places, mostly in Knightswood Shopping Centre, an area comprising around 10 shops. There are also some shops on Alderman Road, both at Dyke Road and near the community centre.^[63] Trinley Brae Allotments (between Knightswood Road and Turret Crescent) provide space for local residents to grow their own fruit, vegetables and flowers. Children's & Youth Clubs are operated locally for school age children on Thursdays in the south of the area at the Congregational church^[64] and Fridays in the North at the Baptist Church.^[30]

Several denominations of churches are situated in the area of Knightswood Cross (junction of Knightswood Road and Great Western Road). The Church of Scotland is represented locally by St. David's Parish Church^[32] and St. Margaret's Parish Church. Knightswood Baptist Church has been at its current site since 1929.^[30] Episcopalian (now closed),^[65] Roman Catholic,^[33] United Free Church of Scotland^[66] and Free Church of Scotland (Continuing)^[67] churches are all nearby. Low Knightswood is served by Knightswood Congregational church^[64]

• Glasgow tower blocks

•   Media related to Knightswood at Wikimedia Commons
• Knightswood Library and Learning Centre
• About the area – Knightswood Community Council