L-AP4 (L-2-amino-4-phosphonobutyric acid) is a drug used in scientific research, which acts as a group-selective agonist for the group III metabotropic glutamate receptors (mGluR4/6/7/8). It was the first ligand found to act as an agonist selective for this group of mGlu receptors,[1] but does not show selectivity between the different mGluR Group III subtypes. It is widely used in the study of this receptor family and their various functions.[2][3][4][5]
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Other names | L-2-Amino-4-phosphonobutyric acid |
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ECHA InfoCard | 100.164.384 |
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Formula | C4H10NO5P |
Molar mass | 183.100 g·mol−1 |
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