Lipoma-preferred partner is a protein that in humans is encoded by the LPP gene.[5][6]
LPP | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | LPP, LIM domain containing preferred translocation partner in lipoma | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 600700 MGI: 2441849 HomoloGene: 4075 GeneCards: LPP | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Lipoma-preferred partner is a subfamily of LIM domain proteins that are characterized by an N-terminal proline rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease related chromosomal translocations which result in the expression of fusion proteins that may promote tumor growth.[6]
This article incorporates text from the United States National Library of Medicine, which is in the public domain.