Large subunit ribosomal ribonucleic acid (LSU rRNA) is the largest of the two major RNA components of the ribosome. Associated with a number of ribosomal proteins, the LSU rRNA forms the large subunit of the ribosome. The LSU rRNA acts as a ribozyme, catalyzing peptide bond formation.
LSU rRNA | |
---|---|
Identifiers | |
Symbol | LSU |
Rfam | CL00112 |
Other data | |
PDB structures | PDBe |
Type | LSU rRNA size | Species | Length | Accession | Reference |
---|---|---|---|---|---|
Bacterial (Prokaryotic) | 23S | Escherichia coli | 2,905 nt | NR_076322.1 | [1] |
Archaeal (Prokaryotic) | 23S | Halobacterium salinarum | 2,906 nt | NR_076247.1 | [2] |
Eukaryotic | 5.8S & 28S | Homo sapiens | 157 + 5,025 nt | NR_145821.1; M11167.1 | [3][4] |
Mitochondrial | 16S | Homo sapiens | 1,559 nt | NC_012920.1 | [5][6] |
Plastid | 23S | Arabidopsis thaliana | 2,810 nt | NC_000932.1 | [7] |
LSU rRNA sequences are widely used for working out evolutionary relationships among organisms, since they are of ancient origin and are found in all known forms of life.