Lanthanum carbonate

Summary

Lanthanum carbonate, La2(CO3)3, is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal (bastnäsite), along with monazite.

Lanthanum carbonate
Names
IUPAC name
Lanthanum carbonate
Identifiers
  • 587-26-8 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL2096647 checkY
ChemSpider
  • 147758 checkY
ECHA InfoCard 100.008.728 Edit this at Wikidata
EC Number
  • 209-599-5
  • 168924
UNII
  • 0M78EU4V9H checkY
  • DTXSID30890512 Edit this at Wikidata
  • InChI=1S/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6 checkY
    Key: NZPIUJUFIFZSPW-UHFFFAOYSA-H checkY
  • InChI=1/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6
    Key: NZPIUJUFIFZSPW-CYFPFDDLAT
  • [La+3].[La+3].O=C([O-])[O-].[O-]C([O-])=O.[O-]C([O-])=O
Properties
La2(CO3)3
Molar mass 457.838 g/mol
Appearance White powder, hygroscopic
Density 2.6–2.7 g/cm3
Melting point decomposes
negligible
Solubility soluble in acids
Pharmacology
V03AE03 (WHO)
Related compounds
Other anions
Lanthanum(III) oxide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Chemistry edit

Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example

Medical uses edit

Lanthanum carbonate is used in medicine as a phosphate binder.[1] As a medication it is sold under the trade name Fosrenol by the pharmaceutical company Shire Pharmaceuticals. Due to its large size (1000 mg tablet is 2.2 cm in diameter), it may be possible to choke on the tablet if it is not chewed. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. For cats with hyperphosphatemia it is available under the trade name Renalzin by Bayer Animal Health.[2]

However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral edema, should be clinically monitored.[3]

Other applications edit

Lanthanum carbonate is also used for the tinting of glass,[citation needed] for water treatment, and as a catalyst for hydrocarbon cracking.

References edit

  1. ^ Editorial Staff (December 2004). "Lanthanum Carbonate". All Micromedex Systems. Micromedex, Inc. Archived from the original on 2007-09-14. Retrieved 2007-11-25.
  2. ^ Bayer Animal Health (26 September 2008). "Bayer Animal Health launches Renalzin for Cats" (PDF). Archived from the original (PDF) on 7 July 2011. Retrieved 2008-09-30.
  3. ^ Tonelli, Marcello; Pannu, Neesh; Manns, Braden (2010). "Oral Phosphate Binders in Patients with Kidney Failure". New England Journal of Medicine. 362 (14): 1312–24. doi:10.1056/NEJMra0912522. PMID 20375408. S2CID 22322676.

External links edit

  • Lanthanum - medlineplus.org
  • Fosrenol.com - the manufacturer's web site
  • Fosrenol - Drugs.com
  • Fosrenol - Medscape.com
  • PhosphorusControl.com - PhosphorusControl.com
  • Bayer Animal Health