Keating was born in St. Paul, Minnesota.^[1]

On April 6, 1937, Keating created Professor Puzzlewit, a quiz program on KMJ radio in Fresno, California, and Blue Network west coast network. He also was the program's quizmaster.^[2][3]

Keating was an announcer for NBC in the 1940s, an announcer for ABC radio's This Is Your FBI from 1945 to 1953, and a regular on the short-lived series The Hank McCune Show. Keating was the longest of several actors to play neighbor Harry Morton on The George Burns and Gracie Allen Show. Keating took over the role of Harry Morton from Fred Clark in 1953 and continued in this role on the short-lived sequel, The George Burns Show.

During his first episode on The Burns and Allen Show, George Burns stopped the action just before Harry's entrance and explained that Clark had left the show. Then he introduced Larry Keating to Bea Benaderet who played Blanche Morton saying, "This is Larry Keating and he is going to be your husband now". The pair greeted and complimented each other on their previous work. George remarked that if they are going to be so nice to each other, no one will believe they are married.^{[citation needed]}

Keating played Roger Addison, the next door neighbor (of Wilbur Post, who was played by Alan Young) on the television series Mister Ed from 1961 until his death in 1963.

Keating's film credits include The Mating Season (1951), When Worlds Collide (1951), Monkey Business (1952), and Inferno (1953).

Keating was diagnosed with leukemia in February 1963 while Season 3 of Mister Ed was in production. Despite his illness, Keating returned to the series when filming began for the fourth season that summer. He filmed three episodes for Season 4 and worked up to the week before his death on August 26, 1963.^[4] His final movie role was in The Incredible Mr. Limpet. He is entombed in Portland, Oregon's Mount Calvary Cemetery.^{[citation needed]}

• Larry Keating at IMDb
• Larry Keating at AllMovie
• Larry Keating at Rotten Tomatoes
• Larry Keating at Find a Grave