Lesia is a feminine given name. Notable people with the name include:

• Lesia Dychko (born 1939), Ukrainian music educator and composer
• Lesia Liss (born 1966), American politician
• Lesia Tsurenko (born 1989), Ukrainian tennis player
• Lesia Valadzenkava (born 1991), Belarusian ice dancer
• Lesia Vasylenko (born 1987), Ukrainian lawyer and politician

Other uses:

• Lesia (plant), a genus of plants in the family Gesneriaceae
• LESIA, a French space and astrophysics instrumentation research laboratory