Levopropylhexedrine (Eventin) is an adrenergic alkylamine used as an anorectic in Germany[1][2] and patented by Smith Kline & French in 1947.[3] It has also been used in the anticonvulsant preparation barbexaclone in combination with phenobarbital to offset sedation.[4][5][6] Levopropylhexedrine is the levorotatory S-enantiomer of propylhexedrine. The dextrorotatory counterpart is known as dextropropylhexedrine.
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Routes of administration | Oral |
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ECHA InfoCard | 100.025.678 |
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Formula | C10H21N |
Molar mass | 155.285 g·mol−1 |
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The enantiopure synthesis of levopropylhexedrine may be accomplished in a two step reaction. The first step is the Wenker synthesis of the relevant aziridine. The second step is the simple catalytic hydrogenation of the propylhexedrine-aziridine.[7]