For former companies, see navigation box at the bottom of page.

• A.L. Simpkin & Co. Ltd - confectionery producer
• Ancon Building Products - specialist stainless steel brickwork supports
• Arnold Laver - UK HQ - timber importer and merchants
• AMK Fencing - Civil engineering and fencing
• Arthur Price & Co. - cutlery manufacturers
• ARUP - engineering consultancy
• B. Braun - UK HQ, medical appliances and surgical instruments manufacturer
• Company of Cutlers in Hallamshire
• DavyMarkham Ltd - HQ - construction engineering
• Department for Work and Pensions - civil service
• Digital Solutions Global Ltd - IT and Project Management services delivery
• Fluent, Inc. European HQ - computer simulation of fluid dynamics (CFD)
• Forgemasters - HQ for Sheffield Forgemasters International Ltd.
• Gripple - producers of fencing materials
• Henry Boot PLC - FTSE-listed construction company
• Insight Enterprises - computer hardware suppliers
• Irwin Mitchell - HQ of top 50 law firm
• John Wilson - manufacturer of ice skating blades
• Kelham island brewery - micro brewery
• Land Instruments International - manufacturer of industrial infrared temperature measurement devices and gas analysers
• Littlefish - managed IT services
• NAVCA - National Association for Voluntary and Community Action, the national body for Third Sector local infrastructure organisations in England
• OCLC (UK) Ltd. - library automation systems
• Outokumpu (Avesta Polarit) - UK HQ, stainless steel distributor
• Parexel - clinical trials contracts, statistical analysis
• Planet X Bikes - professional bike retailer and manufacturer
• Richlyn Systems - software and website developers
• Razor - AI, Data & Software Consultancy. Manufacturing software author of MIP
• SDL International - translation software
• SIG plc - HQ, European supplier of insulation, roofing and commercial interiors
• Spear & Jackson International Ltd -HQ - hand tool manufacturers
• Sumo Digital - games (formerly Infogrames and Gremlin)
• Swann Morton - manufacturer of surgical scalpels
• The Boeing Company - aerospace manufacturer
• Twinkl - online educational publishing house
• Ufi Ltd - EGovernment Online training organisation
• UK Visas and Immigration - part of the Home Office
• WANdisco - software producers
• Warp Records - independent record label, who also set up:
  • Bleep.com - an online record-store
  • Warp Films - their film division
• William Stones Ltd - now defunct brewers

• ARM Holdings
• Autodesk - CAD software
• Aviva (formerly Norwich Union - call centre)
• BT Group - call centre and local network administration; Plusnet subsidiary HQ
• Cap Gemini - data (Rotherham)
• Capita - public sector outsourcing
• DLA Piper Rudnick Gray Cary - international law firm (branch office)
• DXC Technology - IT consulting
• George Wimpey - area office, national house builder
• HSBC - bank's national IT centre, and underground data centre at Tankersley
• IBM - IT consulting
• McLaren Automotive - British automotive manufacturer (Corporate Office and Composites Technology Centre located on Seldon Way, Catcliffe, Sheffield S60 5XA)
• Mondelēz International - liquorice allsorts, Jelly Babies, wine gums etc factory
• Nabarro LLP - law firm
• Nationwide Building Society - building society call centre
• NXP Semiconductors - chip design
• Primetals Technologies - mining technology
• Tata Steel Europe - steel maker (bought Corus Group)
• Tesco - regional distribution centre (Clowne)
• Virgin Media - formerly Telewest Broadband, flagship call centre

• Economy of Sheffield