This is a list of mayors of the city of Eugene, Oregon. The years following each name denote each mayor's term in office.

• J. B. Underwood (1864–1869)^[1] (official office name at the time: President of the Board of Trustees)
• A. S. Patterson (1869–1873)^[1]
• Joel Ware (1873–1875)^[1]
• Benjamin Franklin Dorris (1875–1877)^[1]
• George B. Dorris (1877–1879)^[1][2]
• Benjamin Franklin Dorris (1879–1881)^[1]
• Thomas Grundy Hendricks (1881–1883)^[1][3]
• G. B. Dunn (1883–1885)^[1]
• Francis Berrian Dunn (1885–1889)^[1][4]
• Albert Gallitin Hovey (1889–1891)^[1][5]
• John Henry McClung (1891–1893)^[1][6]
• Sam H. Friendly (1893–1895)^[1]
• Joseph DeWitt Matlock (1895–1897)^[1]
• William F. Kuykendall (1897–1899)^[1]
• Tom W. Harris (1899–1901)^[1]
• Gabriel Russell Chrisman (1901–1905)^[1]
• Francis Marion Wilkins (1905–1907)^[1][7]
• Joseph DeWitt Matlock (1907–1910)^[1]
• Frank J. Berger (1910–1913)^[1][8][9]
• Darwin E. Yoran (1913–1915)^[1][8]
• W. A. Bell (1915–1917)^[1]
• Charles O. Peterson (1917–1923)^[1][10]
• Edwin B. Parks (1923–1925)^[1][11]
• Ernest U. Lee (1925–1927)^[1][12]
• Alex L. Williamson (1927–1929)^[1][13]
• Howard E. Wilder (1929–1932)^[1][14]
• Elisha Large (1932–1945)^[1][15]
• Earl L. McNutt (1945–1949)^[1]
• Victor Edwin Johnson (1949–1956)^[1]
• John Joseph McGinty (1957–1958)^[16]
• Edwin Earl Cone (1958–1968)^[17]
• Les Anderson (1969–1977)^[18][19]
• Gus Keller (1977–1984)^[20]
• Brian Obie (1985–1988)
• Jeffrey Miller (1989–1992)^[21]
• Ruth Bascom (1993–1996)^[22]
• Jim Torrey (1997–2004)
• Kitty Piercy (2005–2017)
• Lucy Vinis (2017–present)