• Roy Baumeister – psychologist of self-control
• Konrad E. Bloch – Nobel Prize-winning biochemist, who helped learn about the functioning of cholesterol
• Mark Frederick Boyd - malariologist and writer
• James M. Buchanan – winner of Nobel Prize in economics
• Talbot "Sandy" D'Alemberte – attorney, civil-rights activist, former dean of the Florida State University Law School, former president of Florida State University, president of the American Bar Association and the American Judicature Society
• Paul Dirac – Nobel Prize-winning physicist whose theories predicted antimatter
• Sylvia Earle – former chief scientist for the U.S. National Oceanic and Atmospheric Administration
• Neil Frank – former director of the National Hurricane Center
• Fred Gainous – former president of Florida A & M University, 2002–2004; former chancellor of the Alabama College System's Department of Postsecondary Education; associate vice president of St. Petersburg College
• Robert A. Holton – chemist and inventor of Taxol
• Tim Howard – president and founder of Cambridge Graduate University international, former head of doctorate program of Law & Policy at Northeastern University, former Assistant Attorney General of Florida
• Sir Harold Kroto – Nobel Prize-winning chemist who helped discover fullerenes
• Max Mayfield – former director of the National Hurricane Center
• Alfred Mele – philosopher of free will
• Robert S. Mulliken – physicist and chemist who won both the Priestley Medal and the Nobel Prize
• Michel Oksenberg – China scholar, member of National Security Council
• X. William Proenza – former director of the National Hurricane Center
• Michael Ruse – philosopher, historian of science, noteworthy atheist
• Robert Schrieffer – Nobel Laureate, BCS Theory of Superconductivity
• E. Lee Spence – underwater archeologist
• G. Gabrielle Starr – president of Pomona College^[1]

Space exploration edit

• Carolyn S. Griner – former director of the NASA Marshall Space Flight Center
• Winston Scott – NASA astronaut
• Norman Thagard – NASA astronaut; flew on three different U.S. Space Shuttles, and on one Russian mission to the Mir space station

• Jesse Bullington – Fantasy novelist; also published as Alex Marshall
• Robert Olen Butler – Pulitzer Prize-winning author for A Good Scent from a Strange Mountain (fiction)
• Lisa De Pasquale – political writer and columnist
• Doug Marlette – Pulitzer Prize-winning cartoonist
• Leora Bettison Robinson (1840-1914) – author, educator
• Jeff Shaara – New York Times bestselling author of historical fiction
• Michael Shaara – Pulitzer prize-winning author (for The Killer Angels)
• Jeff VanderMeer – World Fantasy Award-winning author (for the novella The Transformation of Martin Lake)

• Jerrie Mock – aviator and first woman to fly around the world solo

• Wally Amos – founder of the "Famous Amos" chocolate chip cookie brand; actor
• Eugene Figg – engineer for such bridges as Sunshine Skyway Bridge, Linn Cove Viaduct, and Natchez Trace Parkway Bridge
• Robert B. Hilton – Tallahassee newspaper owner and Confederate congressman during the American Civil War

• Red Barber – sportscaster, Radio Hall of Fame member
• Jim Cramer – host of CNBC's Mad Money

Acting edit

• Kay Aldridge – model and actress
• Matt Battaglia – actor and former NFL player
• Cathy Jenéen Doe – actress
• Brad Davis – actor (Midnight Express, Querelle)
• Kyan Douglas – the "grooming expert" from Queer Eye for the Straight Guy
• Faye Dunaway – actress, Academy Award winner for Network
• Tony Hale – actor, played Byron "Buster" Bluth on Arrested Development
• Cheryl Hines – actress, two-time Emmy nominee for Curb your Enthusiasm, director, married to Robert F. Kennedy, Jr.
• Polly Holliday – actress, Golden Globe winner (for television series Alice)
• Will Kirby – Big Brother 2 (2001) winner
• Christine Lahti – film actress and director, winner of Academy Award for Leiberman in Love, two Golden Globes and Emmy for Chicago Hope
• Burt Reynolds – Emmy and Golden Globe Award-winning, Oscar-nominated actor, attended FSU
• Anika Noni Rose – Tony Award-winning actress, as Emmie Thibodeaux in Caroline, or Change
• Sonny Shroyer – actor who played deputy sheriff on The Dukes of Hazzard
• Roy Wood, Jr. – comedian and actor on The Daily Show

Writing and production edit

• Jim Butterworth – documentary filmmaker, winner of DuPont-Columbia Award for Seoul Train
• Ron J. Friedman – writer of Disney's Academy Award-nominated film Brother Bear

• Art Agnos – former mayor of San Francisco, California
• Reubin Askew – politician, former governor of Florida
• Bobby Brantley – lieutenant governor of Florida 1987–1991
• Lawton Chiles – politician and FSU research fellow; former US Senator and Governor of Florida
• LeRoy Collins – politician and Governor of Florida; the only Tallahassee native to serve as Florida's governor
• Parris Glendening – former Governor of Maryland
• Carla Hayden – 14th Librarian of Congress
• Scott Maddox – former mayor of Tallahassee
• John Marks – Mayor of Tallahassee 2003-2014
• Kenneth Minihan – former director of the National Security Agency
• Nell Foster Rogers – lobbyist
• Orson Swindle – commissioner of the Federal Trade Commission
• Gregory Tony (born 1978) – Sheriff of Broward County, Florida
• Craig Waters – spokesman for the Florida Supreme Court

• Catherine Willis Gray Murat – great-grandniece of George Washington
• Prince Achille Murat – nephew of Napoleon Bonaparte
• Charles Kenzie Steele – clergyman and civil rights activist
• Ernest I. Thomas – raiser of the original flag at Iwo Jima^[2]

• Marshall Ledbetter – protester who took over the Florida capitol building

• Luh Tyler – rapper, songwriter
• Cannonball Adderley – jazz alto saxophone player, Grammy Award winner
• Nat Adderley – jazz cornet and trumpet player
• Ethel Cain (Hayden Anhedönia) – singer-songwriter, artist
• George Clinton – musician, founder of Funk bands Parliament and Funkadelic
• Rita Coolidge – Grammy Award-winning singer, "From the Bottle to the Bottom" and "Lover Please"
• Janice Harsanyi – vocalist and teacher
• Kenny Howes – rock musician
• K. Michelle (born Kimberly Michelle Pate) – reality TV personality and R&B singer
• Jim Morrison – lead singer and lyricist of The Doors
• Marcus Roberts – jazz pianist
• T-Pain (born Faheem Najm) – hip hop and R&B singer
• Butch Trucks (Claude Hudson Trucks) – drummer, member of the Allman Brothers band
• Mayday Parade - Formed in 2005, the band was a result of a merger between two local Tallahassee bands, Kid Named Chicago and Defining Moment.

Composition edit

• Creed – rock band formed in Tallahassee
• Carlisle Floyd – opera composer, Susannah (1955) and others
• Marcus Roberts – jazz pianist, composer and music professor at Florida State University
• Morgan Sorne – singer-songwriter
• Ernst von Dohnányi – composer and pianist
• Ellen Taaffe Zwilich – Pulitzer prize-winning composer (for Three Movements for Orchestra (Symphony No. 1))

• David Ross (baseball) – MLB catcher
• Robert "Bobby" C. Bowden – college football coach, winner of two national championships
• Ricky Carmichael – motocross/supercross champion
• Kevin Carter – NFL defensive end
• Bradley Cooper – member of 1984 and 1988 Bahamas Summer Olympics team
• Gene Cox – State of Florida Sports Hall of Fame member (Leon High School football coach)^[3]
• Antonio Cromartie – NFL player credited with the longest play in NFL history
• Kim Crosby – NASCAR driver, with a best race finish of 20th, in 2004
• Dwight F. Davis – founder of the international tennis Davis Cup
• Walter Dix – U.S. track team member and medalist at 2008 Beijing Olympics
• Warrick Dunn – FSU and NFL football star
• Carrie Englert (Zimmerman) – member of 1976 U.S. Summer Olympics team^[4]
• Corey Fuller – played for FSU's football team, later became a wide receiver for the Vikings, Browns and Ravens
• Michael Gaines – tight end for the Detroit Lions
• DaVanche (Ron) Galimore – member of 1980 U.S. Summer Olympics team^[4]
• Willie Galimore – member of College Football Hall of Fame, and NFL football player
• William Gay – NFL cornerback for the Pittsburgh Steelers
• Althea Gibson – winner of several Wimbledon and US Open tennis championships
• Frances C. Griscom – U.S. Women's amateur golf champion
• Ken Harnden – hurdler and sprinter who represented Zimbabwe in the 1996 and 2000 Olympic Games
• Tahesia Harrigan – professional sprinter (BVI)
• Bob Hayes – sprinter and gold medal winner on 1964 U.S. Summer Olympics team; NFL football wide receiver for Dallas Cowboys
• Missy Hyatt – professional wrestling valet and commentator for World Championship Wrestling and Extreme Championship Wrestling
• Taylor Jacobs – professional football player, wide receiver with Washington Redskins, San Francisco 49ers, and Denver Broncos
• Marty Jannetty – professional wrestler, best known for his work with WWE
• Reggie Jefferson – MLB player
• Brad Johnson – NFL quarterback
• Brandy Johnson – member of 1988 U.S. Summer Olympics team
• Desmond Koh – amateur swimmer who represented Singapore in the 1988, 1992, and 1996 Olympic Games
• Nevin McCaskill – NFL player for the Green Bay Packers
• Mike "11" Martin – All-Time winningest coach in NCAA Division I College Baseball; 2019 inductee in National College Baseball Hall of Fame
• Michelle McCool – World Wrestling Entertainment diva (formally Diva Champion)
• Fondren Mitchell – football player
• Brian Olson – member of 1996, 2000 and 2004 U.S. Summer Olympics teams^[5]
• Burgess Owens – professional football player, member of Oakland Raider team that won Super Bowl XV
• Bill Peterson – college and NFL head football coach
• Zach Piller – NFL guard for the Tennessee Titans
• Don Pumphrey, Jr – offensive tackle for the Tampa Bay Buccaneers^[6]
• Elise Ray – gymnast, represented United States in 2000 Olympic Games
• Gabrielle Reece – professional volleyball player, model
• Deion Sanders – FSU football star, NFL cornerback, Major League Baseball outfielder, NFL Network commentator
• Ernie Sims – NFL linebacker
• Dwight Smith – MLB outfielder
• Bobby Thigpen – MLB relief pitcher and coach
• Craphonso Thorpe – NFL wide receiver
• Marion Tinsley – world checkers champion 1955–58, 1975–91
• Charlie Ward – 1993 Heisman Trophy winner
• Pat Watkins – NFL safety for the Dallas Cowboys
• Chris Weinke – 2000 Heisman Trophy winner
• Boo Williams – NFL tight end for the New Orleans Saints
• Jameis Winston – 2014 Heisman winner and quarterback for the Tampa
• Woody Woodward – MLB shortstop - Braves, Reds; FSU Baseball Head Coach (1975–78); MLB GM - Yankees, Phillies, Mariners
• Wally Williams – NFL (1993-2003) Cleveland Browns, Baltimore Ravens, and New Orleans Saints (First Franchise Player in Ravens History)

• Karl Zerbe – expressionist painter using the encaustic painting technique