Luna – A synthetically produced family in a futuristic urban habitat.
Making History- Sitcom about unlikely friends engaging in time-travel.
Marvin Marvin – An teenage alien from the planet Klooton goes to Earth to protect himself from evil invaders, starring Lucas Cruikshank, However, the show received negative reviews and got cancelled after one season.
Meego – Children's show in which a shape-shifting alien lives with a family.
Metal Mickey – kids' show in which a wise-cracking robot lives with a family.
The Middleman – Based on a comic, it is about a secret organization that takes care of science fiction themed threats.
Mike & Angelo – an alien comes to Earth and inadvertently causes chaos and havoc to the family he lives with.
OK Computer - India's first science fiction comedy series about ethics related to Artificial Intelligence.
The Orville – (2017-present) 1-hour episodic sci-fi dramedy, created by Seth MacFarlane, about the titular U.S.S. Orville (a mid-level exploratory space vessel in service to the Planetary Union; a 25th-century interstellar state encompassing Earth and many other worlds).
Other Space – It follows a young and inexperienced crew as they adventure into an unknown universe to face mysterious clouds, food and fuel shortages, robot rebellions, folds in time, and the occasional alien attack.
Red Dwarf – (1988-1999, 2012-present) Eclectic survivors aboard a mining ship marooned 3 million years' travel from the solar system to return to Earth.
Rick and Morty – Adult animated series about the misadventures of alcoholic scientist Rick and his easily influenced grandson Morty, who split their time between domestic family life and intergalactic space travel.
Robert's Robots - British kids' comedy about a man who makes various humanoid robots.
The Second Hundred Years – Sitcom about a prospector frozen via cryogenics, then brought back to live with his much older son and grandson his own age (played by the same actor).
The Spaceship – Radio sitcom set on a spaceship in 2104, looking for alien life.
The Strangerers – Two highly eccentric alien agents on an equally eccentric alternative Earth; ends on an unresolved cliffhanger.
They Came From Outer Space – Two alien brothers from the planet Crouton ditch on their parents plans to send them to Cambridge University, instead going to California to live by the beach and learn about humans (especially females). They're chased by two bumbling Air Force members intent on their study.
Small Wonder – (1984–1989) About a father who invents a robot child.