Between 1978 - 1983 Scott played as a goalkeeper for Leyton Orient Watford and Blackpool.^[2] He also played for Dagenham FC (now Dagenham and Redbridge FC).

After surviving leukaemia, Scott has raised more than £10 million for a number of charitable causes, through what he calls "alternative charity fundraising events", including the following:

• April 1989: London Marathon – Just three weeks before life saving bone marrow transplant for leukaemia
• April 1990: London Marathon – Less than a year after transplant to show there is 'life after leukaemia'.
• October 1992: Snowdonia Marathon – Britain's toughest marathon
• November 1993: Everest Marathon – Staged 18,000 feet up the world's highest peak
• August 1995: Abseiled down a giant piece the size of Blackpool Tower
• September 1995: Complete Olympic distance triathlon
• March 1996: Firewalk over burning coals
• April 1996: Completed London Marathon in polar expedition gear
• May 1996: Sahara Marathon des Sables – 150-mile ultra marathon carrying all equipment.
• Oct – Jan 96–97: Scott 2 the South Pole – Expedition to the South Pole
• March 1997: 125-mile Devizes to Westminster canoe marathon
• July 1997: Fastnet yacht race
• September 1997: Climbed Kilimanjaro
• July 1998: Completed 135-mile Death Valley ultra marathon in 140 degrees of heat
• April 1999: Expedition to the North Pole.
• Feb 2001: Climbed Aconcagua, Argentina (22,841 ft)
• October 2001: 168 km Jordan Desert Cup ultra marathon – dressed as Indiana Jones
• April 2002: London Marathon in deep-sea diving suit – Taking 5 days, 8 hours, 29 mins and 46 seconds to complete
• November 2002: New York City Marathon in deep-sea diving suit – again finishing on the sixth day
• June 2003: Edinburgh Marathon in deep-sea diving suit – this time taking 6 days 4 hours, 30 mins and 56 seconds
• August 2003: Completed the Marathon of Britain – 175-mile ultra marathon
• September 2003: Completed Great North Run in deep-sea diving suit
• October 2003: Completed the world's first underwater marathon in deep-sea diving suit in Loch Ness – taking 12 days, raising £1.1 million.
• Feb 2004: First person to watch a film underwater, watching 'Finding Nemo' DVD in tank at the London Aquarium
• July 2004: Sport Relief Challenge – walked to top of BT Tower London in deep-sea diving suit
• Oct–Dec 2004: Cycled penny-farthing across Australia – Perth to Sydney, nearly 3,000 miles taking 50 days
• May 2005: 'Swam' from John O'Groats to Land's End in swimming pool on back of a lorry, taking 12 days
• September 2005: Completed Great North Run in Apollo 17 spacesuit on bouncy stilts
• April 2006: Completed London Marathon as St George in 100 lb suit of armour, pulling 200 lb dragon, taking over eight days. Helped Sir Steve Redgrave break world fundraising record of £1.8 million
• April 2007: Completed London Marathon as Indiana Jones – 'chased' (but really pulling) 350 lb boulder around course
• May 2007: Trekked the Inca trail to Machu Picchu
• April 2008: London Marathon as Iron Giant – 9 feet tall robot, weighing 70 lbs, on stilts taking 6 days
• April 2009: London Marathon as The Beatles (Sgt Pepper uniforms) in the Yellow Submarine
• July – Sept 2009: Land's End to John O'Groats walk with life size tyrannosaurus rex – 'T-Rex Treks' taking 72 days, raising £175,000 for Teenage Cancer Trust
• June 2010: World's deepest underground marathon, 12,000 feet down at bottom of world's deepest mine in, South Africa – severe heat and humidity over two miles underground
• April – May 2011: Magic Marathon – dragged around London Marathon as Brian the Snail from the Magic Roundabout, taking 27 days
• May – June 2012: Completed Diamond Jubilee Marathon in deep sea diving suit on behalf of The Queen Elizabeth Diamond Jubilee Trust, becoming the first person to complete London 2012 Olympic Marathon course.
• Oct 2013 - Completes climb of internal staircase of the 'Gherkin' building wearing deep-sea diving suit in 2 hours 53 minutes - a Guinness World Record.
• May 2014: Completed the Maldon mud race in a deep-sea diving suit.
• March - Sept 2018 Suffers from heart arrhythmia and undergoes ablation
• October 2020 - Completes 3 Peaks Challenge (Ben Nevis, Scafell Pike and Snowdon) wearing deep-sea diving suit, taking 10 days, raising £163,000 for The Lord's Taverners.
• March 2021 - Undergoes throat surgery - diagnosed with synovial sarcoma
• Aug 2022 - Sarcoma recurs - undergoes extensive surgery (13 1/2 operation) to remove sarcoma
• April 2023 - Completes London Marathon as 'resconstructible' Captain Scarlet
• May 2023 - Completes London - Essex 100 mile bike ride
• Sept 2024 - Diagnosed with synovial sarcoma in lung and leg - immediately completes London Vitality 10K as Indiana Jones

Scott has been injured during some of his events. For example, he injured his shoulder during the underwater marathon when he fell off a 15-foot (4.6 m) ledge while in the loch.

After being awarded an MBE in 2005, Scott joked that the award should stand for "Mad, Bonkers and Eccentric". He was awarded an Honorary Fellowship from the University of East London in 2003 and the Freedom of the London Borough of Havering in 2009.

In total Scott has undergone over 30 operations for a number of injuries and also life-saving surgeries.

• "Marathon man erodes lead boots" – BBC News
• Lloyd Scott interview on his trek from Land's End to John O'Groats
• "Tyrannosaurus! TREKS!" – Blackpool Gazette
• Profile at The Old Boys Network