Lucio Marineo Siculo (Vizzini, 1444 or 1445 – Spain, 1533) was a Sicilian humanist, historian and poet, known as a prominent figure of the Spanish Renaissance.

Lucio Marineo Siculo
Born	1444 or 1445 Vizzini, Kingdom of Sicily
Died	1533 (aged 88–89) Kingdom of Spain
Nationality	Sicilian
Occupation(s)	humanist, historian

He first taught Greek and Latin literature in Palermo. He moved to Spain and taught for twelve years at the University of Salamanca. His teaching and books influenced the development of the Spanish Renaissance, and his disciples included Alfono de Segura. King Ferdinand brought him to the royal court to serve as chaplain and chronicler. He was also charged with the education of the children of the nobility.