MGS-0039 is a drug that is used in neuroscientific research, which acts as a potent and selective antagonist for group II of the metabotropic glutamate receptors (mGluR2/3).[1][2] It produces antidepressant and anxiolytic effects in animal studies,[3][4][5][6] and has been shown to boost release of dopamine and serotonin in specific brain areas.[7][8] Research has suggested this may occur through a similar mechanism as that suggested for the similarly glutamatergic drug ketamine.[9][10]
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Formula | C15H14Cl2NO5 |
Molar mass | 359.18 g·mol−1 |
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