MK-886, or L-663536, is a leukotriene antagonist. It may perform this by blocking the 5-lipoxygenase activating protein (FLAP), thus inhibiting 5-lipoxygenase (5-LOX),[1] and may help in treating atherosclerosis.[2]
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Preferred IUPAC name
3-{3-(tert-Butylsulfanyl)-1-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1H-indol-2-yl}-2,2-dimethylpropanoic acid | |
Other names
L-663536
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Identifiers | |
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3D model (JSmol)
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MeSH | L+663536 |
PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C27H34ClNO2S | |
Molar mass | 472.083 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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