MRGPRX1 Knowpia

MRGPRX1
Identifiers
Aliases	MRGPRX1, GPCR, MGRG2, MRGX1, SNSR4, MAS related GPR family member X1
External IDs	OMIM: 607227 MGI: 2441674 HomoloGene: 86246 GeneCards: MRGPRX1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	18,939,414 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	48,207,834 bp
RNA expression pattern
	Top expressed in
	lower lobe of lung; ; liver; ; canal of the cervix; ; skin of abdomen;
	Top expressed in
	zone of skin; ; lip; ; white adipose tissue; ; urinary bladder; ; esophagus; ; quadriceps femoris muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity; G protein-coupled receptor activity; transmembrane signaling receptor activity;
Cellular component	plasma membrane; membrane; integral component of membrane; integral component of plasma membrane; cell surface;
Biological process	acute-phase response; G protein-coupled receptor signaling pathway; signal transduction; cell surface receptor signaling pathway; response to chloroquine;
	Sources:Amigo / QuickGO
Orthologs
	259249
	243979
	ENSG00000170255
	ENSMUSG00000050425
	Q96LB2
	Q3KNA1
	NM_147199; NM_001393578
	NM_175531
	NP_671732
	NP_780740
	Wikidata
View/Edit Human	View/Edit Mouse

Mas-related G-protein coupled receptor member X1 is a protein that in humans is encoded by the MRGPRX1 gene.^[5]^[6]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000170255 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000050425 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Dong X, Han S, Zylka MJ, Simon MI, Anderson DJ (Sep 2001). "A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons". Cell. 106 (5): 619–32. doi:10.1016/S0092-8674(01)00483-4. PMID 11551509. S2CID 14119088.
^ "Entrez Gene: MRGPRX1 MAS-related GPR, member X1".

Lembo PM, Grazzini E, Groblewski T, et al. (2002). "Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs". Nat. Neurosci. 5 (3): 201–9. doi:10.1038/nn815. PMID 11850634. S2CID 42544746.
Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Galés C, Rebois RV, Hogue M, et al. (2005). "Real-time monitoring of receptor and G-protein interactions in living cells". Nat. Methods. 2 (3): 177–84. doi:10.1038/nmeth743. PMID 15782186. S2CID 22398051.