mRNA-5671 also known as V941 is a cancer vaccine candidate developed by Moderna.[1] It is a tetravalent vaccine that targets G12D, G12V, G13D or G12C driver mutations in the KRAS gene.[2] It is currently being evaluated for the treatment of either non-small cell lung cancer, colorectal cancers with microsatellite instability, or pancreatic adenocarcinoma, all with confirmed KRAS driver mutations.[3]
Vaccine description | |
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Target | Cancer driven by G12D, G12V, G13D or G12C mutation in the KRAS gene |
Vaccine type | mRNA |
Clinical data | |
Routes of administration | Intramuscular |
ATC code |
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