Madonna and Child with Saints is an oil-on-panel painting by Lorenzo Lotto, signed "L. Lotus F.[ecit]", and created c. 1505.^[1] It was first definitively recorded in 1727, when it was in France in the Orléans Collection. It is now in the Scottish National Gallery in Edinburgh.^[2] It is in the Holy Conversation style – on the left are a male saint (a prophet or St Jerome, holding a scroll) and Saint Peter, whilst to the left are a female saint (possibly Clare of Assisi) and Francis of Assisi.^[3]