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Mannosulfan

Summary

Mannosulfan (INN) is an alkylating agent with the potential for the treatment of cancer. It is not approved by the United States FDA for cancer treatment. Research suggests it is less toxic than the alkyl sulfonate Busulfan.[1]

Mannosulfan
Clinical data
Other names[(2R,3S,4S,5R)-3,4-dihydroxy-2,5,6-tris(methylsulfonyloxy)hexyl] methanesulfonate
ATC code
Identifiers
  • 1,2,5,6-Tetrakis-O-(methylsulfonyl)-D-mannitol
CAS Number
  • 7518-35-6 checkY
PubChem CID
  • 24140
ChemSpider
  • 16736959
UNII
  • 135FQ40L36
Chemical and physical data
FormulaC10H22O14S4
Molar mass494.51 g·mol−1
3D model (JSmol)
  • Interactive image
  • CS(=O)(=O)OC[C@H]([C@H]([C@@H]([C@@H](COS(=O)(=O)C)OS(=O)(=O)C)O)O)OS(=O)(=O)C
  • InChI=1S/C10H22O14S4/c1-25(13,14)21-5-7(23-27(3,17)18)9(11)10(12)8(24-28(4,19)20)6-22-26(2,15)16/h7-12H,5-6H2,1-4H3/t7-,8-,9-,10-/m1/s1
  • Key:UUVIQYKKKBJYJT-ZYUZMQFOSA-N
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References edit

  1. ^ Jeswani G, Paul SD (2017). "Recent Advances in the Delivery of Chemotherapeutic Agents". Nano- and Microscale Drug Delivery Systems. pp. 281–98. doi:10.1016/B978-0-323-52727-9.00015-7. ISBN 978-0-323-52727-9.

External links edit

  •   Media related to Mannosulfan at Wikimedia Commons