Margaretha Maria Antonetta Neefjes, born in Noordwijk, 21 November 1941, married sculptor Heppe de Moor (1938 - 1992). They had two daughters: writer Marente and visual artist Lara. After junior high and the Hogere Burgerschool she attended the Royal Conservatory of The Hague, where she studied piano and singing. Afterward she studied art history and archeology in Amsterdam and taught piano. With her husband, she began an artist salon in 1984 in 's-Graveland.

De Moor began writing, and after a failed attempt at a novel, debuted with a story collection, Op de rug gezien; the collection won her a literary award, the Gouden Ezelsoor, and a nomination for the AKO Literatuurprijs. Many of her works have been translated into German.

• 1989 – Gouden Ezelsoor, nomination for AKO Literatuurprijs for Op de rug gezien
• 1990 – Lucy B. en C.W. van der Hoogt-prijs for Dubbelportret
• 1992 – AKO Literatuurprijs for Eerst grijs dan wit dan blauw

• Op de rug gezien (stories, 1988)
• Dubbelportret (novellas, 1989)
• Eerst grijs dan wit dan blauw (novel, 1991)
• De virtuoos (novel, 1993)
• Ik droom dus (stories, 1995)
• Hertog van Egypte (novel, 1996)
• Zee-Binnen (novel, 1999)
• Verzamelde verhalen (stories, 2000)
• Kreutzersonate - Een liefdesverhaal (novel, 2001)
• Ze waren schoolmeesters (biography, 2001)
• De verdronkene (novel, 2005)
• De Kegelwerper (novel, 2006)
• Als een hond zijn blinde baas (essays, 2007)
• De schilder en het meisje (novel, 2010)
• De verdronkene (novel, 2010)
• Mélodie d'amour (novel, 2013)

• (in Dutch) Margriet de Moor at Digital Library for Dutch Literature