Sofia's husband Rico, was a drunk and a bum and didn't work to support the family. This is why Sofia had to work in place of her husband just to make ends meet. In spite of this, Sofia's husband was able to accuse her of adultery and took off with their only daughter, Milagros. Sofia then, went after her husband but before being able to confront him, the husband was run over by a bus.

Not to be dismayed, Sofia went off to Manila in search for her lost child. Little did she know that her daughter was adopted by a famous actress named Divina Miguel whose motives for the child was a political move to increase hype for her new movie.

Sofia, having been gifted with an angelic voice, was discovered by a talent manager and eventually became a famous singer-actress. The point came where Sofia's popularity overshadowed Divina's and to make things worst, Ramon, Divina's love team, tied the knot with Sofia and left Divina. This made Divina Miguel furious and from then on considered Sofia as her mortal enemy. Dreading Sofia for taking away everything from her, Divina directed her anger towards her poor adopted child Bea (Milagros).

At times, Divina would think about her child that she gave away for her career. Divina was disowned by her aunt Donya Felisa when she became pregnant. What Divina doesn't know is that the child she gave away fell under the care of Delia (the maid of Donya Felisa). This child is Charie. Divina was maltreating Charie as she's just a maid's daughter, not knowing that it was her own child.

However, when Donya Felisa died, Divina would plot to acquire her aunt's wealth against Irene who is her aunt's adopted child and happens to be Sofia's long lost sister.

Main cast edit

• Dina Bonnevie as Sofia Catacutan
• Albert Martinez as Ramon Suarez
• Cherie Gil as Divina Miguel
• Celia Rodriguez as Conchita Suarez
• Angelu de Leon as Irene Buencamino
• Kim delos Santos as Charie Miguel
• Anne Curtis as Bea Miguel
• Michael Flores as Dennis Suarez
• Bojo Molina as Marcus Paredes
• Dino Guevarra as Ricky
• Chubi del Rosario as Leslie

Supporting cast edit

• Rosemarie Gil as Rodora Suarez
• Aiza Marquez as Trina Suarez
• Maui Taylor as Ruthy
• Maureen Mauricio as Delia
• Patricia Javier as Vivian Paredes
• Ricardo Cepeda as Fidel
• Vanna Garcia as Sharon
• Jackie Castillejo as Carla
• My-My Davao as Patty
• Katya Santos as Tricia
• Phillip Lazaro as Freddie
• Leni Santos as Helen
• Daniel Fernando as Rico Catacutan

Extended cast edit

• Wendy Fernando as Mylene
• Jacklyn Kate as Wendy
• Polo Ravales as Michael
• Ivan Gonzales as Andrei
• Daria Ramirez as Belinda
• Pocholo Montes as Delfin
• Mike Lloren as Leo

Minor Cast/Special Participation edit

• Marita Zobel as Doña Felisa
• Ryan Eigenmann as Dave
• Benjie Felipe as Kidnapper
• Harlene Bautista as Annie

Directed by: Gil Tejada Jr.

Headwriter: RJ Nuevas

Writers: Suzette Doctolero, Patricia Valenzuela

• May Bukas Pa by Wency Cornejo (main theme) - Originally performed by Rico J. Puno
• Save This Heart by Lani Misalucha (closing theme)
• Kung Wala Na by Jaya (closing theme)
• Bakit Iniwan by Freestyle (closing theme)
• Breathless by The Corrs - used by Girls can Sing (Anne Curtis, Aiza Marquez, Vanna Garcia, Maui Taylor) in the contest they joined

• May Bukas Pa at IMDb  
• May Bukas Pa
• NEW TV SHOW: Hectic montage of births, adoptions launches 'May Bukas Pa'
• CHERIE GIL IN RP FOR NEW TV SERIES
• RICKY LO'S UPDATE ON CHERIE HILL