Members of this genus typically have shortened elytra and lack functional wings. They are often iridescent blue, green, or black with pits/punctures on the elytra and thorax, and a bloated abdomen. Some species of males have kinks in their antennae, which are shaped differently for different species.

As with all other members of Meloidae, the larval cycle is hypermetamorphic; the larva goes through several body types, the first of which is typically a mobile triungulin that finds and attaches to a host in order to gain access to the host's offspring. They usually climb onto a flower head, and await a bee there. They will then attach themselves to the bee. If it is a male, they wait for mating with a female. They will switch to the female when this takes place. If the bee is a female, however, she will take them back to her nest unwittingly. Once in the nest, the larvae morphs into a grub-like "couch potato" and feeds upon all of the provisions and the larva. Next, they form a pupa and emerge in various seasons depending on the species. Each species of Meloe may attack only a single species or genus of bees. Some are generalists. Though sometimes considered parasitoids, it appears that in general, the Meloe larva consumes the bee larva along with its provisions, and can often survive on the provisions alone; thus they do not truly qualify for this designation (see Parasitoid for definition).

Upon surfacing from their underground lives as larvae, the adults feed on plants in the Ranunculaceae, Ipomoaceae, and Solanaceae families.

Mating begins when a male mounts a female and releases chemical components through the kinks on the antennae, massaging her antennae and pulling them back. This serves to calm the female. Mating then occurs, with the male transferring his cantharidin to the female during this period and she coats her eggs with it. ^[2]

The following species are recognised in the genus Meloe:^[3][4]

•   Media related to Meloe at Wikimedia Commons