A destitute Marthe Preston is in dire straits in Paris until gambler Richard Dorval comes to her aid. In gratitude, she agrees to a scheme of Dorval's to seduce and wed his rival, "Diamond Johnny" Silk, then help ruin Johnny's horse-racing business interests.

Marthe's inside information enables Dorval and an accomplice, bookie Joe Farley, to bribe Johnny's jockeys to deliberately lose races or to help them influence the odds. Johnny learns the truth and demands she leave. Martha has fallen in love with her husband, however, so she pretends to go along with a plot to poison Johnny's horse, double-crossing Dorval and rejoicing in Johnny's triumph.

• Ricardo Cortez as Johnny Silk
• Mary Astor as Marthe Preston Silk
• John Halliday as Richard Dorval
• Ralph Ince as Joe Farley
• Kitty Kelly as Gertie Robbins
• James Donlan as Clark
• George Davis as The Frenchman

Uncredited:

• Herman Bing as Fritz Tannenbaum
• André Cheron as French Detective
• Jean De Briac as Hotel Manager
• Tom Herbert as One of Johnny's Bookies
• John Larkin as Black Horse Handler
• Tom McGuire as Race Track Bookie
• Frank Mills as Tony - One of Johnny's Bookies

• List of films about horse racing

• Men of Chance at IMDb  
• Men of Chance at AllMovie
• Men of Chance at the TCM Movie Database
• Men of Chance at the American Film Institute Catalog