Menthoxypropanediol

Summary

Menthoxypropanediol (also known as Cooling agent 10 [tradename of Takasago]), is a synthetic derivative of menthol. While the cooling strength of 3-(l-menthoxy)propane-1,2-diol is accepted as being about 20–25% that of menthol, it is also noted that "in a Vaseline ointment, 3-(l-menthoxy)propane-1,2-diol shows a cool feeling 2.0 to 2.5 times stronger than that of l-menthol". It is used in various cosmetic chemical concoctions.[1]

Menthoxypropanediol
Stereo skeletal formula of menthoxypropanediol ((1R,2S,5R)-5-meth,-2-prop,-yl)
Names
IUPAC name
Menthoxypropanediol
Identifiers
  • 207792-35-6 checkY
  • 87061-04-9 (non-specific) checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 4515105 checkY
  • 13136530 (2S,5R)-5-meth,-2-prop,-yl checkY
  • 5254045 (1R,2S,5R)-5-meth,-2-prop,-yl checkY
ECHA InfoCard 100.081.149 Edit this at Wikidata
EC Number
  • 289-296-2
  • 2463
MeSH 3-Menthoxypropane-1,2-diol
  • 5362595
  • 16006278 (2S,5R)-5-meth,-2-prop,-yl
  • 6850757 (1R,2S,5R)-5-meth,-2-prop,-yl
  • 44467722 (1S,2R,5S)-5-meth,-2-prop,-yl
  • 15195782 (2S)-2-ol, (1R,2S,5R)-5-meth,-2-prop,-yl
UNII
  • KD6TZ2QICH checkY
  • DTXSID20868962 Edit this at Wikidata
  • InChI=1S/C13H26O3/c1-9(2)12-5-4-10(3)6-13(12)16-8-11(15)7-14/h9-15H,4-8H2,1-3H3 checkY
    Key: MDVYIGJINBYKOM-UHFFFAOYSA-N checkY
  • CC(C)C1CCC(C)CC1OCC(O)CO
Properties
C13H26O3
Molar mass 230.348 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References edit

  1. ^ Leffingwell & Associates. "Cooler Than Menthol". Retrieved 2008-06-14.